Clonal architectures predict clinical outcome in clear cell renal cell carcinoma

Clonal architectures predict clinical outcome in clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is a urogenital cancer with a well-defined genetic landscape. Here, the authors analyse the clonal architecture of ccRCC patients from three populations, and find prognostic subtypes linked to immune infiltrates and clonal architecture.

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Autores principales: Yi Huang, Jiayin Wang, Peilin Jia, Xiangchun Li, Guangsheng Pei, Changxi Wang, Xiaodong Fang, Zhongming Zhao, Zhiming Cai, Xin Yi, Song Wu, Baifeng Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/6e325ecbfb32442eb1a9e808c83d9a19
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spelling oai:doaj.org-article:6e325ecbfb32442eb1a9e808c83d9a192021-12-02T16:50:59ZClonal architectures predict clinical outcome in clear cell renal cell carcinoma10.1038/s41467-019-09241-72041-1723https://doaj.org/article/6e325ecbfb32442eb1a9e808c83d9a192019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09241-7https://doaj.org/toc/2041-1723Clear cell renal cell carcinoma (ccRCC) is a urogenital cancer with a well-defined genetic landscape. Here, the authors analyse the clonal architecture of ccRCC patients from three populations, and find prognostic subtypes linked to immune infiltrates and clonal architecture.Yi HuangJiayin WangPeilin JiaXiangchun LiGuangsheng PeiChangxi WangXiaodong FangZhongming ZhaoZhiming CaiXin YiSong WuBaifeng ZhangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yi Huang
Jiayin Wang
Peilin Jia
Xiangchun Li
Guangsheng Pei
Changxi Wang
Xiaodong Fang
Zhongming Zhao
Zhiming Cai
Xin Yi
Song Wu
Baifeng Zhang
Clonal architectures predict clinical outcome in clear cell renal cell carcinoma
description Clear cell renal cell carcinoma (ccRCC) is a urogenital cancer with a well-defined genetic landscape. Here, the authors analyse the clonal architecture of ccRCC patients from three populations, and find prognostic subtypes linked to immune infiltrates and clonal architecture.
format article
author Yi Huang
Jiayin Wang
Peilin Jia
Xiangchun Li
Guangsheng Pei
Changxi Wang
Xiaodong Fang
Zhongming Zhao
Zhiming Cai
Xin Yi
Song Wu
Baifeng Zhang
author_facet Yi Huang
Jiayin Wang
Peilin Jia
Xiangchun Li
Guangsheng Pei
Changxi Wang
Xiaodong Fang
Zhongming Zhao
Zhiming Cai
Xin Yi
Song Wu
Baifeng Zhang
author_sort Yi Huang
title Clonal architectures predict clinical outcome in clear cell renal cell carcinoma
title_short Clonal architectures predict clinical outcome in clear cell renal cell carcinoma
title_full Clonal architectures predict clinical outcome in clear cell renal cell carcinoma
title_fullStr Clonal architectures predict clinical outcome in clear cell renal cell carcinoma
title_full_unstemmed Clonal architectures predict clinical outcome in clear cell renal cell carcinoma
title_sort clonal architectures predict clinical outcome in clear cell renal cell carcinoma
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/6e325ecbfb32442eb1a9e808c83d9a19
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AT jiayinwang clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
AT peilinjia clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
AT xiangchunli clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
AT guangshengpei clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
AT changxiwang clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
AT xiaodongfang clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
AT zhongmingzhao clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
AT zhimingcai clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
AT xinyi clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
AT songwu clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
AT baifengzhang clonalarchitecturespredictclinicaloutcomeinclearcellrenalcellcarcinoma
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