Nicotinamide riboside kinase structures reveal new pathways to NAD+.

Nicotinamide riboside kinase structures reveal new pathways to NAD+.

The eukaryotic nicotinamide riboside kinase (Nrk) pathway, which is induced in response to nerve damage and promotes replicative life span in yeast, converts nicotinamide riboside to nicotinamide adenine dinucleotide (NAD+) by phosphorylation and adenylylation. Crystal structures of human Nrk1 bound...

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Bibliographic Details
Main Authors: Wolfram Tempel, Wael M Rabeh, Katrina L Bogan, Peter Belenky, Marzena Wojcik, Heather F Seidle, Lyudmila Nedyalkova, Tianle Yang, Anthony A Sauve, Hee-Won Park, Charles Brenner
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2007
Subjects:
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/6e381eb8f8a6473f955a9c049c6e9369
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https://doaj.org/article/6e381eb8f8a6473f955a9c049c6e9369

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