Amniotic epithelial cells from the human placenta potently suppress a mouse model of multiple sclerosis.
Human amniotic epithelial cells (hAEC) have stem cell-like features and immunomodulatory properties. Here we show that hAEC significantly suppressed splenocyte proliferation in vitro and potently attenuated a mouse model of multiple sclerosis (MS). Central nervous system (CNS) CD3(+) T cell and F4/8...
Enregistré dans:
Auteurs principaux: | Yu Han Liu, Vijesh Vaghjiani, Jing Yang Tee, Kelly To, Peng Cui, Ding Yuan Oh, Ursula Manuelpillai, Ban-Hock Toh, James Chan |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2012
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/6e3a963e955e4e66ab94f88a15e7d859 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Changes in culture expanded human amniotic epithelial cells: implications for potential therapeutic applications.
par: Gita Pratama, et autres
Publié: (2011) -
Human amniotic epithelial cell transplantation induces markers of alternative macrophage activation and reduces established hepatic fibrosis.
par: Ursula Manuelpillai, et autres
Publié: (2012) -
Anti-inflammatory effects of adult stem cells in sustained lung injury: a comparative study.
par: Yuben Moodley, et autres
Publié: (2013) -
Hematopoietic potential of mouse placenta with the application of placenta flushing
par: WEI,BIN, et autres
Publié: (2008) -
Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta.
par: Hélène Bierne, et autres
Publié: (2012)