FREQUENCY AND ANTIBIOGRAM OF ENTEROPATHOGENIC ESCHERICHIA COLI FROM A TERTIARY CARE HOSPITAL IN PAKISTAN

Objective: To determine the frequency and antibiogram of Enteropathogenic Escherichia coli in children less than two years. Study Design: Cross-sectional study. Place and Duration of Study: The study was conducted at the department of microbiology, Army Medical College, Rawalpindi (NUMS) Pakis...

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Autores principales:	Mehreen Gilani, Mahwish Latif, Nazish Babar, Mehwish Gillani, Sara Najeeb, Amira Hafeez
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2019
Materias:	drug resistance enteropathogenic escherichia coli (epec) Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/6e3ff96a0dda40caa915663863c37bf8
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spelling	oai:doaj.org-article:6e3ff96a0dda40caa915663863c37bf82021-11-11T03:20:12ZFREQUENCY AND ANTIBIOGRAM OF ENTEROPATHOGENIC ESCHERICHIA COLI FROM A TERTIARY CARE HOSPITAL IN PAKISTAN0030-96482411-8842https://doaj.org/article/6e3ff96a0dda40caa915663863c37bf82019-08-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/3195/2304https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the frequency and antibiogram of Enteropathogenic Escherichia coli in children less than two years. Study Design: Cross-sectional study. Place and Duration of Study: The study was conducted at the department of microbiology, Army Medical College, Rawalpindi (NUMS) Pakistan, from Jul 2013 to Feb 2014. Material and Methods: Stool samples collected from children with diarrhea who were below 2 years of age were included. Escherichia.coli isolates were identified by microscopy, culture and biochemical reactions (API 10S). Among the Escherichia coli isolates, EPEC isolates were identified by serogrouping. Antibiotic susceptibility of EPEC isolates was determined by modified Kirby-Bauer disk diffusion method according to CLSI guidelines. Results: A total of 42 EPEC isolates were collected during the study period. None of the isolates were sensitive to ampicillin followed by ciprofloxacin (52.4%), ceftriaxone (7.3%), co-trimoxazole (12.5%), amikacin (87.5%), co-amoxiclav (9.5%), aztreonam (15%), meropenem (100%), sulbactum-cefoperazone (97.2%), piperacillintazobactam (89.5%), and gentamicin (63.4%). About 97% of the isolates were multidrug resistant. Conclusion: EPEC is an important pathogen in pediatric diarrhea with very high rate of multi drug resistance.Mehreen GilaniMahwish LatifNazish BabarMehwish GillaniSara NajeebAmira HafeezArmy Medical College Rawalpindiarticledrug resistanceenteropathogenic escherichia coli (epec)MedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 69, Iss 4, Pp 758-762 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	drug resistance enteropathogenic escherichia coli (epec) Medicine R Medicine (General) R5-920
spellingShingle	drug resistance enteropathogenic escherichia coli (epec) Medicine R Medicine (General) R5-920 Mehreen Gilani Mahwish Latif Nazish Babar Mehwish Gillani Sara Najeeb Amira Hafeez FREQUENCY AND ANTIBIOGRAM OF ENTEROPATHOGENIC ESCHERICHIA COLI FROM A TERTIARY CARE HOSPITAL IN PAKISTAN
description	Objective: To determine the frequency and antibiogram of Enteropathogenic Escherichia coli in children less than two years. Study Design: Cross-sectional study. Place and Duration of Study: The study was conducted at the department of microbiology, Army Medical College, Rawalpindi (NUMS) Pakistan, from Jul 2013 to Feb 2014. Material and Methods: Stool samples collected from children with diarrhea who were below 2 years of age were included. Escherichia.coli isolates were identified by microscopy, culture and biochemical reactions (API 10S). Among the Escherichia coli isolates, EPEC isolates were identified by serogrouping. Antibiotic susceptibility of EPEC isolates was determined by modified Kirby-Bauer disk diffusion method according to CLSI guidelines. Results: A total of 42 EPEC isolates were collected during the study period. None of the isolates were sensitive to ampicillin followed by ciprofloxacin (52.4%), ceftriaxone (7.3%), co-trimoxazole (12.5%), amikacin (87.5%), co-amoxiclav (9.5%), aztreonam (15%), meropenem (100%), sulbactum-cefoperazone (97.2%), piperacillintazobactam (89.5%), and gentamicin (63.4%). About 97% of the isolates were multidrug resistant. Conclusion: EPEC is an important pathogen in pediatric diarrhea with very high rate of multi drug resistance.
format	article
author	Mehreen Gilani Mahwish Latif Nazish Babar Mehwish Gillani Sara Najeeb Amira Hafeez
author_facet	Mehreen Gilani Mahwish Latif Nazish Babar Mehwish Gillani Sara Najeeb Amira Hafeez
author_sort	Mehreen Gilani
title	FREQUENCY AND ANTIBIOGRAM OF ENTEROPATHOGENIC ESCHERICHIA COLI FROM A TERTIARY CARE HOSPITAL IN PAKISTAN
title_short	FREQUENCY AND ANTIBIOGRAM OF ENTEROPATHOGENIC ESCHERICHIA COLI FROM A TERTIARY CARE HOSPITAL IN PAKISTAN
title_full	FREQUENCY AND ANTIBIOGRAM OF ENTEROPATHOGENIC ESCHERICHIA COLI FROM A TERTIARY CARE HOSPITAL IN PAKISTAN
title_fullStr	FREQUENCY AND ANTIBIOGRAM OF ENTEROPATHOGENIC ESCHERICHIA COLI FROM A TERTIARY CARE HOSPITAL IN PAKISTAN
title_full_unstemmed	FREQUENCY AND ANTIBIOGRAM OF ENTEROPATHOGENIC ESCHERICHIA COLI FROM A TERTIARY CARE HOSPITAL IN PAKISTAN
title_sort	frequency and antibiogram of enteropathogenic escherichia coli from a tertiary care hospital in pakistan
publisher	Army Medical College Rawalpindi
publishDate	2019
url	https://doaj.org/article/6e3ff96a0dda40caa915663863c37bf8
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FREQUENCY AND ANTIBIOGRAM OF ENTEROPATHOGENIC ESCHERICHIA COLI FROM A TERTIARY CARE HOSPITAL IN PAKISTAN

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