Brachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions

Beatrice Y Brewington,1 Yusra F Shao,2 Fredrick H Davidorf,1 Colleen M Cebulla1 1Havener Eye Institute, Department of Ophthalmology and Visual Science, Ohio State University, 2Medical Student Research Program, The Ohio State University College of Medicine, Columbus, OH, USA Abstract: Surgical mana...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Brewington BY, Shao YF, Davidorf FH, Cebulla CM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Brachytherapy for UM Uveal melanoma UM Fine needle aspiration biopsy Genetic prognostic testing in UM patients Molecular markers of metastasis Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/6e561f2eeb344cf4840e1afb31c130af
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6e561f2eeb344cf4840e1afb31c130af
record_format	dspace
spelling	oai:doaj.org-article:6e561f2eeb344cf4840e1afb31c130af2021-12-02T05:13:54ZBrachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions1177-5483https://doaj.org/article/6e561f2eeb344cf4840e1afb31c130af2018-05-01T00:00:00Zhttps://www.dovepress.com/brachytherapy-for-patients-with-uveal-melanoma-historical-perspectives-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Beatrice Y Brewington,1 Yusra F Shao,2 Fredrick H Davidorf,1 Colleen M Cebulla1 1Havener Eye Institute, Department of Ophthalmology and Visual Science, Ohio State University, 2Medical Student Research Program, The Ohio State University College of Medicine, Columbus, OH, USA Abstract: Surgical management with enucleation was the primary treatment for uveal melanoma (UM) for over 100 years. The Collaborative Ocular Melanoma Study confirmed in 2001 that globe-preserving episcleral brachytherapy for UM was safe and effective, demonstrating no survival difference with enucleation. Today, brachytherapy is the most common form of radiotherapy for UM. We review the history of brachytherapy in the treatment of UM and the evolution of the procedure to incorporate fine-needle-aspiration biopsy techniques with DNA- and RNA-based genetic prognostic testing. Keywords: brachytherapy, uveal melanoma, UM, fine-needle-aspiration biopsy, genetic prognostic testing, molecular markersBrewington BYShao YFDavidorf FHCebulla CMDove Medical PressarticleBrachytherapy for UMUveal melanomaUMFine needle aspiration biopsyGenetic prognostic testing in UM patientsMolecular markers of metastasisOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 925-934 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Brachytherapy for UM Uveal melanoma UM Fine needle aspiration biopsy Genetic prognostic testing in UM patients Molecular markers of metastasis Ophthalmology RE1-994
spellingShingle	Brachytherapy for UM Uveal melanoma UM Fine needle aspiration biopsy Genetic prognostic testing in UM patients Molecular markers of metastasis Ophthalmology RE1-994 Brewington BY Shao YF Davidorf FH Cebulla CM Brachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions
description	Beatrice Y Brewington,1 Yusra F Shao,2 Fredrick H Davidorf,1 Colleen M Cebulla1 1Havener Eye Institute, Department of Ophthalmology and Visual Science, Ohio State University, 2Medical Student Research Program, The Ohio State University College of Medicine, Columbus, OH, USA Abstract: Surgical management with enucleation was the primary treatment for uveal melanoma (UM) for over 100 years. The Collaborative Ocular Melanoma Study confirmed in 2001 that globe-preserving episcleral brachytherapy for UM was safe and effective, demonstrating no survival difference with enucleation. Today, brachytherapy is the most common form of radiotherapy for UM. We review the history of brachytherapy in the treatment of UM and the evolution of the procedure to incorporate fine-needle-aspiration biopsy techniques with DNA- and RNA-based genetic prognostic testing. Keywords: brachytherapy, uveal melanoma, UM, fine-needle-aspiration biopsy, genetic prognostic testing, molecular markers
format	article
author	Brewington BY Shao YF Davidorf FH Cebulla CM
author_facet	Brewington BY Shao YF Davidorf FH Cebulla CM
author_sort	Brewington BY
title	Brachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions
title_short	Brachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions
title_full	Brachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions
title_fullStr	Brachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions
title_full_unstemmed	Brachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions
title_sort	brachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/6e561f2eeb344cf4840e1afb31c130af
work_keys_str_mv	AT brewingtonby brachytherapyforpatientswithuvealmelanomahistoricalperspectivesandfuturetreatmentdirections AT shaoyf brachytherapyforpatientswithuvealmelanomahistoricalperspectivesandfuturetreatmentdirections AT davidorffh brachytherapyforpatientswithuvealmelanomahistoricalperspectivesandfuturetreatmentdirections AT cebullacm brachytherapyforpatientswithuvealmelanomahistoricalperspectivesandfuturetreatmentdirections
_version_	1718400476734554112

Brachytherapy for patients with uveal melanoma: historical perspectives and future treatment directions

Ejemplares similares