$Refractive status at birth: its relation to newborn physical parameters at birth and gestational age.$
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Refractive status at birth: its relation to newborn physical parameters at birth and gestational age.

<h4>Background</h4>Refractive status at birth is related to gestational age. Preterm babies have myopia which decreases as gestational age increases and term babies are known to be hypermetropic. This study looked at the correlation of refractive status with birth weight in term and pret...

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Autores principales:	Raji Mathew Varghese, Vishnubhatla Sreenivas, Jacob Mammen Puliyel, Sara Varughese
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2009
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6e5ac6591d4c49c5989b407068462771
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spelling	oai:doaj.org-article:6e5ac6591d4c49c5989b4070684627712021-11-25T06:17:19ZRefractive status at birth: its relation to newborn physical parameters at birth and gestational age.1932-620310.1371/journal.pone.0004469https://doaj.org/article/6e5ac6591d4c49c5989b4070684627712009-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19214228/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Refractive status at birth is related to gestational age. Preterm babies have myopia which decreases as gestational age increases and term babies are known to be hypermetropic. This study looked at the correlation of refractive status with birth weight in term and preterm babies, and with physical indicators of intra-uterine growth such as the head circumference and length of the baby at birth.<h4>Methods</h4>All babies delivered at St. Stephens Hospital and admitted in the nursery were eligible for the study. Refraction was performed within the first week of life. 0.8% tropicamide with 0.5% phenylephrine was used to achieve cycloplegia and paralysis of accommodation. 599 newborn babies participated in the study. Data pertaining to the right eye is utilized for all the analyses except that for anisometropia where the two eyes were compared. Growth parameters were measured soon after birth. Simple linear regression analysis was performed to see the association of refractive status, (mean spherical equivalent (MSE), astigmatism and anisometropia) with each of the study variables, namely gestation, length, weight and head circumference. Subsequently, multiple linear regression was carried out to identify the independent predictors for each of the outcome parameters.<h4>Results</h4>Simple linear regression showed a significant relation between all 4 study variables and refractive error but in multiple regression only gestational age and weight were related to refractive error. The partial correlation of weight with MSE adjusted for gestation was 0.28 and that of gestation with MSE adjusted for weight was 0.10. Birth weight had a higher correlation to MSE than gestational age.<h4>Conclusion</h4>This is the first study to look at refractive error against all these growth parameters, in preterm and term babies at birth. It would appear from this study that birth weight rather than gestation should be used as criteria for screening for refractive error, especially in developing countries where the incidence of intrauterine malnutrition is higher.Raji Mathew VargheseVishnubhatla SreenivasJacob Mammen PuliyelSara VarughesePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 4, Iss 2, p e4469 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Raji Mathew Varghese Vishnubhatla Sreenivas Jacob Mammen Puliyel Sara Varughese Refractive status at birth: its relation to newborn physical parameters at birth and gestational age.
description	<h4>Background</h4>Refractive status at birth is related to gestational age. Preterm babies have myopia which decreases as gestational age increases and term babies are known to be hypermetropic. This study looked at the correlation of refractive status with birth weight in term and preterm babies, and with physical indicators of intra-uterine growth such as the head circumference and length of the baby at birth.<h4>Methods</h4>All babies delivered at St. Stephens Hospital and admitted in the nursery were eligible for the study. Refraction was performed within the first week of life. 0.8% tropicamide with 0.5% phenylephrine was used to achieve cycloplegia and paralysis of accommodation. 599 newborn babies participated in the study. Data pertaining to the right eye is utilized for all the analyses except that for anisometropia where the two eyes were compared. Growth parameters were measured soon after birth. Simple linear regression analysis was performed to see the association of refractive status, (mean spherical equivalent (MSE), astigmatism and anisometropia) with each of the study variables, namely gestation, length, weight and head circumference. Subsequently, multiple linear regression was carried out to identify the independent predictors for each of the outcome parameters.<h4>Results</h4>Simple linear regression showed a significant relation between all 4 study variables and refractive error but in multiple regression only gestational age and weight were related to refractive error. The partial correlation of weight with MSE adjusted for gestation was 0.28 and that of gestation with MSE adjusted for weight was 0.10. Birth weight had a higher correlation to MSE than gestational age.<h4>Conclusion</h4>This is the first study to look at refractive error against all these growth parameters, in preterm and term babies at birth. It would appear from this study that birth weight rather than gestation should be used as criteria for screening for refractive error, especially in developing countries where the incidence of intrauterine malnutrition is higher.
format	article
author	Raji Mathew Varghese Vishnubhatla Sreenivas Jacob Mammen Puliyel Sara Varughese
author_facet	Raji Mathew Varghese Vishnubhatla Sreenivas Jacob Mammen Puliyel Sara Varughese
author_sort	Raji Mathew Varghese
title	Refractive status at birth: its relation to newborn physical parameters at birth and gestational age.
title_short	Refractive status at birth: its relation to newborn physical parameters at birth and gestational age.
title_full	Refractive status at birth: its relation to newborn physical parameters at birth and gestational age.
title_fullStr	Refractive status at birth: its relation to newborn physical parameters at birth and gestational age.
title_full_unstemmed	Refractive status at birth: its relation to newborn physical parameters at birth and gestational age.
title_sort	refractive status at birth: its relation to newborn physical parameters at birth and gestational age.
publisher	Public Library of Science (PLoS)
publishDate	2009
url	https://doaj.org/article/6e5ac6591d4c49c5989b407068462771
work_keys_str_mv	AT rajimathewvarghese refractivestatusatbirthitsrelationtonewbornphysicalparametersatbirthandgestationalage AT vishnubhatlasreenivas refractivestatusatbirthitsrelationtonewbornphysicalparametersatbirthandgestationalage AT jacobmammenpuliyel refractivestatusatbirthitsrelationtonewbornphysicalparametersatbirthandgestationalage AT saravarughese refractivestatusatbirthitsrelationtonewbornphysicalparametersatbirthandgestationalage
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Refractive status at birth: its relation to newborn physical parameters at birth and gestational age.

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