Clinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature

Michelle K Rhee,1 Francis S Mah21Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 2Scripps Clinic Torrey Pines, La Jolla, CA, USAAbstract: To review the literature on the efficacy of cyclosporine (CsA) ophthalmic emulsion 0.05% on symptomatic relief in chronic...

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Autores principales:	Rhee MK, Mah FS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	dry eye cyclosporine symptoms Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/6e5ae26521f94f87bf3bbc8381d395d1
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spelling	oai:doaj.org-article:6e5ae26521f94f87bf3bbc8381d395d12021-12-02T08:34:40ZClinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature1177-5483https://doaj.org/article/6e5ae26521f94f87bf3bbc8381d395d12017-06-01T00:00:00Zhttps://www.dovepress.com/clinical-utility-of-cyclosporine-csa-ophthalmic-emulsion-005-for-sympt-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Michelle K Rhee,1 Francis S Mah21Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 2Scripps Clinic Torrey Pines, La Jolla, CA, USAAbstract: To review the literature on the efficacy of cyclosporine (CsA) ophthalmic emulsion 0.05% on symptomatic relief in chronic dry eye disease. There is consistent evidence of objective improvements in chronic dry eye disease (Schirmer score, corneal and interpalpebral dye staining, and tear breakup time) with CsA, but variable results with symptomatic improvement, possibly due to patient tolerance of CsA, similar comforting effect with artificial tears and CsA vehicle, and the inherent subjective nature of symptom monitoring and analysis. This review explores the literature on CsA with special attention to symptomatic relief.Keywords: dry eye, cyclosporine, symptomsRhee MKMah FSDove Medical Pressarticledry eyecyclosporinesymptomsOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 11, Pp 1157-1166 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	dry eye cyclosporine symptoms Ophthalmology RE1-994
spellingShingle	dry eye cyclosporine symptoms Ophthalmology RE1-994 Rhee MK Mah FS Clinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature
description	Michelle K Rhee,1 Francis S Mah21Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 2Scripps Clinic Torrey Pines, La Jolla, CA, USAAbstract: To review the literature on the efficacy of cyclosporine (CsA) ophthalmic emulsion 0.05% on symptomatic relief in chronic dry eye disease. There is consistent evidence of objective improvements in chronic dry eye disease (Schirmer score, corneal and interpalpebral dye staining, and tear breakup time) with CsA, but variable results with symptomatic improvement, possibly due to patient tolerance of CsA, similar comforting effect with artificial tears and CsA vehicle, and the inherent subjective nature of symptom monitoring and analysis. This review explores the literature on CsA with special attention to symptomatic relief.Keywords: dry eye, cyclosporine, symptoms
format	article
author	Rhee MK Mah FS
author_facet	Rhee MK Mah FS
author_sort	Rhee MK
title	Clinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature
title_short	Clinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature
title_full	Clinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature
title_fullStr	Clinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature
title_full_unstemmed	Clinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature
title_sort	clinical utility of cyclosporine (csa) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/6e5ae26521f94f87bf3bbc8381d395d1
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Clinical utility of cyclosporine (CsA) ophthalmic emulsion 0.05% for symptomatic relief in people with chronic dry eye: a review of the literature

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