Rapid detection of the H275Y oseltamivir resistance mutation in influenza A/H1N1 2009 by single base pair RT-PCR and high-resolution melting.
<h4>Introduction</h4>We aimed to design a real-time reverse-transcriptase-PCR (rRT-PCR), high-resolution melting (HRM) assay to detect the H275Y mutation that confers oseltamivir resistance in influenza A/H1N1 2009 viruses.<h4>Findings</h4>A novel strategy of amplifying a sin...
Enregistré dans:
Auteurs principaux: | Steven Y C Tong, Farshid Dakh, Aeron C Hurt, Yi-Mo Deng, Kevin Freeman, Peter K Fagan, Ian G Barr, Philip M Giffard |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/6e5b1f5b85a949688f884df01347d8af |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
I223R mutation in influenza A(H1N1)pdm09 neuraminidase confers reduced susceptibility to oseltamivir and zanamivir and enhanced resistance with H275Y.
par: Jérome LeGoff, et autres
Publié: (2012) -
Estimating the fitness advantage conferred by permissive neuraminidase mutations in recent oseltamivir-resistant A(H1N1)pdm09 influenza viruses.
par: Jeff Butler, et autres
Publié: (2014) -
Inhibitory activity of selenium nanoparticles functionalized with oseltamivir on H1N1 influenza virus
par: Li Y, et autres
Publié: (2017) -
Serological response in RT-PCR confirmed H1N1-2009 influenza a by hemagglutination inhibition and virus neutralization assays: an observational study.
par: Mark I Chen, et autres
Publié: (2010) -
Environmental levels of the antiviral oseltamivir induce development of resistance mutation H274Y in influenza A/H1N1 virus in mallards.
par: Josef D Järhult, et autres
Publié: (2011)