Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy
Abstract Background Gallbladder cancer (GBC) is known for its high malignancy and multidrug resistance. Previously, we uncovered that impaired integrity and stability of the elongator complex leads to GBC chemotherapy resistance, but whether its restoration can be an efficient therapeutic strategy f...
Enregistré dans:
Auteurs principaux: | Sunwang Xu, Cen Jiang, Ruirong Lin, Xiaopeng Wang, Xiaoqiang Hu, Wei Chen, Xiangjin Chen, Tao Chen |
---|---|
Format: | article |
Langue: | EN |
Publié: |
BMC
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/6e5dfc5d99824e50897f13ed8078313d |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Insight Between the Epigenetics and Transcription Responding of Cotton Hypocotyl Cellular Elongation Under Salt-Alkaline Stress
par: Cun Rui, et autres
Publié: (2021) -
Biweekly gemcitabine and paclitaxel in patients with relapsed or metastatic squamous cell carcinoma of the head and neck
par: Ammar Sukari, et autres
Publié: (2015) -
Eficacia de gemcitabina en cáncer de vesícula biliar.: Experiencia inicial en cuatro casos
par: Gallardo E,Jorge, et autres
Publié: (2000) -
Circ_0092367 Inhibits EMT and Gemcitabine Resistance in Pancreatic Cancer via Regulating the miR-1206/ESRP1 Axis
par: Shuo Yu, et autres
Publié: (2021) -
Hyaluronan-conjugated liposomes encapsulating gemcitabine for breast cancer stem cells
par: Han NK, et autres
Publié: (2016)