Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy
Abstract Background Gallbladder cancer (GBC) is known for its high malignancy and multidrug resistance. Previously, we uncovered that impaired integrity and stability of the elongator complex leads to GBC chemotherapy resistance, but whether its restoration can be an efficient therapeutic strategy f...
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Auteurs principaux: | , , , , , , , |
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Format: | article |
Langue: | EN |
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BMC
2021
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Accès en ligne: | https://doaj.org/article/6e5dfc5d99824e50897f13ed8078313d |
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