Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy

Abstract Background Gallbladder cancer (GBC) is known for its high malignancy and multidrug resistance. Previously, we uncovered that impaired integrity and stability of the elongator complex leads to GBC chemotherapy resistance, but whether its restoration can be an efficient therapeutic strategy f...

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Auteurs principaux: Sunwang Xu, Cen Jiang, Ruirong Lin, Xiaopeng Wang, Xiaoqiang Hu, Wei Chen, Xiangjin Chen, Tao Chen
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/6e5dfc5d99824e50897f13ed8078313d
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