Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy

Abstract Background Gallbladder cancer (GBC) is known for its high malignancy and multidrug resistance. Previously, we uncovered that impaired integrity and stability of the elongator complex leads to GBC chemotherapy resistance, but whether its restoration can be an efficient therapeutic strategy f...

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Bibliographic Details
Main Authors: Sunwang Xu, Cen Jiang, Ruirong Lin, Xiaopeng Wang, Xiaoqiang Hu, Wei Chen, Xiangjin Chen, Tao Chen
Format: article
Language:EN
Published: BMC 2021
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Online Access:https://doaj.org/article/6e5dfc5d99824e50897f13ed8078313d
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