Multi-hierarchical profiling the structure-activity relationships of engineered nanomaterials at nano-bio interfaces

Understanding nano-bio interactions is key to optimizing the biocompatible design of nanomaterials. Here, the authors combine proteomic and metabolomics studies to evaluate the effect of varying physicochemical properties of iron oxide nanoparticles in macrophage-like cells and mouse lungs.

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Detalles Bibliográficos
Autores principales: Xiaoming Cai, Jun Dong, Jing Liu, Huizhen Zheng, Chitrada Kaweeteerawat, Fangjun Wang, Zhaoxia Ji, Ruibin Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6e6029f21e6544d7be84a96085512496
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Sumario:Understanding nano-bio interactions is key to optimizing the biocompatible design of nanomaterials. Here, the authors combine proteomic and metabolomics studies to evaluate the effect of varying physicochemical properties of iron oxide nanoparticles in macrophage-like cells and mouse lungs.