Clinical applications of corneal confocal microscopy

Mitra Tavakoli1, Parwez Hossain2, Rayaz A Malik11Division of Cardiovascular Medicine, University of Manchester and Manchester Royal Infirmary, Manchester, UK; 2University of Southampton, Southampton Eye Unit, Southampton General Hospital, Southampton, UKAbstract: Corneal confocal microscopy is a nov...

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Autores principales: Mitra Tavakoli, Parwez Hossain, Rayaz A Malik
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2008
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Acceso en línea:https://doaj.org/article/6e606189a38f4ae48946cf7964ead700
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spelling oai:doaj.org-article:6e606189a38f4ae48946cf7964ead7002021-12-02T01:53:07ZClinical applications of corneal confocal microscopy1177-54671177-5483https://doaj.org/article/6e606189a38f4ae48946cf7964ead7002008-06-01T00:00:00Zhttp://www.dovepress.com/clinical-applications-of-corneal-confocal-microscopy-a1798https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Mitra Tavakoli1, Parwez Hossain2, Rayaz A Malik11Division of Cardiovascular Medicine, University of Manchester and Manchester Royal Infirmary, Manchester, UK; 2University of Southampton, Southampton Eye Unit, Southampton General Hospital, Southampton, UKAbstract: Corneal confocal microscopy is a novel clinical technique for the study of corneal cellular structure. It provides images which are comparable to in-vitro histochemical techniques delineating corneal epithelium, Bowman’s layer, stroma, Descemet’s membrane and the corneal endothelium. Because, corneal confocal microscopy is a non invasive technique for in vivo imaging of the living cornea it has huge clinical potential to investigate numerous corneal diseases. Thus far it has been used in the detection and management of pathologic and infectious conditions, corneal dystrophies and ecstasies, monitoring contact lens induced corneal changes and for pre and post surgical evaluation (PRK, LASIK and LASEK, flap evaluations and Radial Keratotomy), and penetrating keratoplasty. Most recently it has been used as a surrogate for peripheral nerve damage in a variety of peripheral neuropathies and may have potential in acting as a surrogate marker for endothelial abnormalities.Keywords: corneal confocal microscopy, cornea, infective keratitis, corneal dystrophy, neuropathy Mitra TavakoliParwez HossainRayaz A MalikDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2008, Iss Issue 2, Pp 435-445 (2008)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Mitra Tavakoli
Parwez Hossain
Rayaz A Malik
Clinical applications of corneal confocal microscopy
description Mitra Tavakoli1, Parwez Hossain2, Rayaz A Malik11Division of Cardiovascular Medicine, University of Manchester and Manchester Royal Infirmary, Manchester, UK; 2University of Southampton, Southampton Eye Unit, Southampton General Hospital, Southampton, UKAbstract: Corneal confocal microscopy is a novel clinical technique for the study of corneal cellular structure. It provides images which are comparable to in-vitro histochemical techniques delineating corneal epithelium, Bowman’s layer, stroma, Descemet’s membrane and the corneal endothelium. Because, corneal confocal microscopy is a non invasive technique for in vivo imaging of the living cornea it has huge clinical potential to investigate numerous corneal diseases. Thus far it has been used in the detection and management of pathologic and infectious conditions, corneal dystrophies and ecstasies, monitoring contact lens induced corneal changes and for pre and post surgical evaluation (PRK, LASIK and LASEK, flap evaluations and Radial Keratotomy), and penetrating keratoplasty. Most recently it has been used as a surrogate for peripheral nerve damage in a variety of peripheral neuropathies and may have potential in acting as a surrogate marker for endothelial abnormalities.Keywords: corneal confocal microscopy, cornea, infective keratitis, corneal dystrophy, neuropathy
format article
author Mitra Tavakoli
Parwez Hossain
Rayaz A Malik
author_facet Mitra Tavakoli
Parwez Hossain
Rayaz A Malik
author_sort Mitra Tavakoli
title Clinical applications of corneal confocal microscopy
title_short Clinical applications of corneal confocal microscopy
title_full Clinical applications of corneal confocal microscopy
title_fullStr Clinical applications of corneal confocal microscopy
title_full_unstemmed Clinical applications of corneal confocal microscopy
title_sort clinical applications of corneal confocal microscopy
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/6e606189a38f4ae48946cf7964ead700
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AT parwezhossain clinicalapplicationsofcornealconfocalmicroscopy
AT rayazamalik clinicalapplicationsofcornealconfocalmicroscopy
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