Aspirin for the Primary Prophylaxis of Colorectal Cancer

Context Increasing epidemic of colorectal cancer worldwide and the expenses of the current screening and treatment of this potentially fatal condition have raised the interest of in finding a primary prophylactic measure. Aspirin has been administrated for more than 40 years to achieve this. Evi...

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Autor principal:	Kamran B Lankarani
Formato:	article
Lenguaje:	EN
Publicado:	Shiraz University of Medical Sciences 2013
Materias:	aspirin colorectal cancer primary prevention Medicine R
Acceso en línea:	https://doaj.org/article/6e61bd91510648cf993d77eb8fb53259
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spelling	oai:doaj.org-article:6e61bd91510648cf993d77eb8fb532592021-11-14T07:53:43ZAspirin for the Primary Prophylaxis of Colorectal Cancer2783-243010.17795/acr-16264https://doaj.org/article/6e61bd91510648cf993d77eb8fb532592013-12-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_45458_225b0ded1a6747b0809ab9a606768aad.pdfhttps://doaj.org/toc/2783-2430Context Increasing epidemic of colorectal cancer worldwide and the expenses of the current screening and treatment of this potentially fatal condition have raised the interest of in finding a primary prophylactic measure. Aspirin has been administrated for more than 40 years to achieve this. Evidence Acquisitions In this manuscript, we reviewed the best available evidence on the prophylatic use of aspirin for colorectal cancer prevention. Results The analysis and large cohort studies revealed that although using ASA would probably decrease the risk of colon cancer, this would not occur before 5-8 years after treatment. ASA usage would increase the risk of major gastrointestinal bleeding. Conclusions Aspirin has been proposed as a chemopreventive agent in colorectal cancer (CRC) for many years, but there are still debates on the proper candidates, treatment time and cost benefit analysis of this potentially harmful drug. This brief review would try to answer these questions using the currently available evidence.Kamran B LankaraniShiraz University of Medical Sciencesarticleaspirincolorectal cancerprimary preventionMedicineRENIranian Journal of Colorectal Research, Vol 1, Iss 3, Pp 7-8 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	aspirin colorectal cancer primary prevention Medicine R
spellingShingle	aspirin colorectal cancer primary prevention Medicine R Kamran B Lankarani Aspirin for the Primary Prophylaxis of Colorectal Cancer
description	Context Increasing epidemic of colorectal cancer worldwide and the expenses of the current screening and treatment of this potentially fatal condition have raised the interest of in finding a primary prophylactic measure. Aspirin has been administrated for more than 40 years to achieve this. Evidence Acquisitions In this manuscript, we reviewed the best available evidence on the prophylatic use of aspirin for colorectal cancer prevention. Results The analysis and large cohort studies revealed that although using ASA would probably decrease the risk of colon cancer, this would not occur before 5-8 years after treatment. ASA usage would increase the risk of major gastrointestinal bleeding. Conclusions Aspirin has been proposed as a chemopreventive agent in colorectal cancer (CRC) for many years, but there are still debates on the proper candidates, treatment time and cost benefit analysis of this potentially harmful drug. This brief review would try to answer these questions using the currently available evidence.
format	article
author	Kamran B Lankarani
author_facet	Kamran B Lankarani
author_sort	Kamran B Lankarani
title	Aspirin for the Primary Prophylaxis of Colorectal Cancer
title_short	Aspirin for the Primary Prophylaxis of Colorectal Cancer
title_full	Aspirin for the Primary Prophylaxis of Colorectal Cancer
title_fullStr	Aspirin for the Primary Prophylaxis of Colorectal Cancer
title_full_unstemmed	Aspirin for the Primary Prophylaxis of Colorectal Cancer
title_sort	aspirin for the primary prophylaxis of colorectal cancer
publisher	Shiraz University of Medical Sciences
publishDate	2013
url	https://doaj.org/article/6e61bd91510648cf993d77eb8fb53259
work_keys_str_mv	AT kamranblankarani aspirinfortheprimaryprophylaxisofcolorectalcancer
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Aspirin for the Primary Prophylaxis of Colorectal Cancer

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