Diversity-oriented functionalization of 2-pyridones and uracils
Diversity-oriented synthesis of 2-pyridone and uracil derivatives is in urgent need in medicinal chemistry as they are useful pharmacophores. Here the authors show that palladium/norbornene cooperative catalysis enabled dual-functionalization of iodinated 2- pyridones and uracils.
Guardado en:
Autores principales: | Yong Shang, Chenggui Wu, Qianwen Gao, Chang Liu, Lisha Li, Xinping Zhang, Hong-Gang Cheng, Shanshan Liu, Qianghui Zhou |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6e648b9aff0148d28469f0aab4b175e1 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Carbamoyl phosphate and its substitutes for the uracil synthesis in origins of life scenarios
por: Louis M. P. Ter-Ovanessian, et al.
Publicado: (2021) -
ABHD5 blunts the sensitivity of colorectal cancer to fluorouracil via promoting autophagic uracil yield
por: Juanjuan Ou, et al.
Publicado: (2019) -
Excitation-dependent fluorescence from atomic/molecular layer deposited sodium-uracil thin films
por: Ville Pale, et al.
Publicado: (2017) -
A New Class of Uracil–DNA Glycosylase Inhibitors Active against Human and Vaccinia Virus Enzyme
por: Inga R. Grin, et al.
Publicado: (2021) -
A 2-Pyridone-Amide Inhibitor Targets the Glucose Metabolism Pathway of <named-content content-type="genus-species">Chlamydia trachomatis</named-content>
por: Patrik Engström, et al.
Publicado: (2015)