Chemical characterization (LC–MS–ESI), cytotoxic activity and intracellular localization of PAMAM G4 in leukemia cells

Abstract Generation 4 of polyamidoamine dendrimer (G4-PAMAM) has several biological effects due to its tridimensional globular structure, repetitive branched amides, tertiary amines, and amino-terminal subunit groups liked to a common core. G4-PAMAM is cytotoxic due to its positive charges. However,...

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Autores principales: R. Flores-Mejía, M. J. Fragoso-Vázquez, L. G. Pérez-Blas, A. Parra-Barrera, S. S. Hernández-Castro, A. R. Estrada-Pérez, J. Rodrígues, E. Lara-Padilla, A. Ortiz-Morales, J. Correa-Basurto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6e664926a0c04ffeb50ba5bbf7433697
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