Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction

Teneurins are cell-cell adhesion receptors that evolved through horizontal gene transfer in which a bacterial YD-repeat protein fused to a eukaryotic receptor. Here the authors present crystallographic and cryo-EM structures of two Teneurins, revealing an ancient YD-repeat protein super-fold.

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Autores principales: Verity A. Jackson, Dimphna H. Meijer, Maria Carrasquero, Laura S. van Bezouwen, Edward D. Lowe, Colin Kleanthous, Bert J. C. Janssen, Elena Seiradake
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6e704646bfad422d89f023858d91ce18
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spelling oai:doaj.org-article:6e704646bfad422d89f023858d91ce182021-12-02T16:49:20ZStructures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction10.1038/s41467-018-03460-02041-1723https://doaj.org/article/6e704646bfad422d89f023858d91ce182018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03460-0https://doaj.org/toc/2041-1723Teneurins are cell-cell adhesion receptors that evolved through horizontal gene transfer in which a bacterial YD-repeat protein fused to a eukaryotic receptor. Here the authors present crystallographic and cryo-EM structures of two Teneurins, revealing an ancient YD-repeat protein super-fold.Verity A. JacksonDimphna H. MeijerMaria CarrasqueroLaura S. van BezouwenEdward D. LoweColin KleanthousBert J. C. JanssenElena SeiradakeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Verity A. Jackson
Dimphna H. Meijer
Maria Carrasquero
Laura S. van Bezouwen
Edward D. Lowe
Colin Kleanthous
Bert J. C. Janssen
Elena Seiradake
Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction
description Teneurins are cell-cell adhesion receptors that evolved through horizontal gene transfer in which a bacterial YD-repeat protein fused to a eukaryotic receptor. Here the authors present crystallographic and cryo-EM structures of two Teneurins, revealing an ancient YD-repeat protein super-fold.
format article
author Verity A. Jackson
Dimphna H. Meijer
Maria Carrasquero
Laura S. van Bezouwen
Edward D. Lowe
Colin Kleanthous
Bert J. C. Janssen
Elena Seiradake
author_facet Verity A. Jackson
Dimphna H. Meijer
Maria Carrasquero
Laura S. van Bezouwen
Edward D. Lowe
Colin Kleanthous
Bert J. C. Janssen
Elena Seiradake
author_sort Verity A. Jackson
title Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction
title_short Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction
title_full Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction
title_fullStr Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction
title_full_unstemmed Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction
title_sort structures of teneurin adhesion receptors reveal an ancient fold for cell-cell interaction
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/6e704646bfad422d89f023858d91ce18
work_keys_str_mv AT verityajackson structuresofteneurinadhesionreceptorsrevealanancientfoldforcellcellinteraction
AT dimphnahmeijer structuresofteneurinadhesionreceptorsrevealanancientfoldforcellcellinteraction
AT mariacarrasquero structuresofteneurinadhesionreceptorsrevealanancientfoldforcellcellinteraction
AT laurasvanbezouwen structuresofteneurinadhesionreceptorsrevealanancientfoldforcellcellinteraction
AT edwarddlowe structuresofteneurinadhesionreceptorsrevealanancientfoldforcellcellinteraction
AT colinkleanthous structuresofteneurinadhesionreceptorsrevealanancientfoldforcellcellinteraction
AT bertjcjanssen structuresofteneurinadhesionreceptorsrevealanancientfoldforcellcellinteraction
AT elenaseiradake structuresofteneurinadhesionreceptorsrevealanancientfoldforcellcellinteraction
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