Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction
Teneurins are cell-cell adhesion receptors that evolved through horizontal gene transfer in which a bacterial YD-repeat protein fused to a eukaryotic receptor. Here the authors present crystallographic and cryo-EM structures of two Teneurins, revealing an ancient YD-repeat protein super-fold.
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Nature Portfolio
2018
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oai:doaj.org-article:6e704646bfad422d89f023858d91ce182021-12-02T16:49:20ZStructures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction10.1038/s41467-018-03460-02041-1723https://doaj.org/article/6e704646bfad422d89f023858d91ce182018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03460-0https://doaj.org/toc/2041-1723Teneurins are cell-cell adhesion receptors that evolved through horizontal gene transfer in which a bacterial YD-repeat protein fused to a eukaryotic receptor. Here the authors present crystallographic and cryo-EM structures of two Teneurins, revealing an ancient YD-repeat protein super-fold.Verity A. JacksonDimphna H. MeijerMaria CarrasqueroLaura S. van BezouwenEdward D. LoweColin KleanthousBert J. C. JanssenElena SeiradakeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Verity A. Jackson Dimphna H. Meijer Maria Carrasquero Laura S. van Bezouwen Edward D. Lowe Colin Kleanthous Bert J. C. Janssen Elena Seiradake Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction |
description |
Teneurins are cell-cell adhesion receptors that evolved through horizontal gene transfer in which a bacterial YD-repeat protein fused to a eukaryotic receptor. Here the authors present crystallographic and cryo-EM structures of two Teneurins, revealing an ancient YD-repeat protein super-fold. |
format |
article |
author |
Verity A. Jackson Dimphna H. Meijer Maria Carrasquero Laura S. van Bezouwen Edward D. Lowe Colin Kleanthous Bert J. C. Janssen Elena Seiradake |
author_facet |
Verity A. Jackson Dimphna H. Meijer Maria Carrasquero Laura S. van Bezouwen Edward D. Lowe Colin Kleanthous Bert J. C. Janssen Elena Seiradake |
author_sort |
Verity A. Jackson |
title |
Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction |
title_short |
Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction |
title_full |
Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction |
title_fullStr |
Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction |
title_full_unstemmed |
Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction |
title_sort |
structures of teneurin adhesion receptors reveal an ancient fold for cell-cell interaction |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/6e704646bfad422d89f023858d91ce18 |
work_keys_str_mv |
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_version_ |
1718383339776245760 |