TLR2, but not TLR4, is required for effective host defence against Chlamydia respiratory tract infection in early life.

TLR2, but not TLR4, is required for effective host defence against Chlamydia respiratory tract infection in early life.

Chlamydia pneumoniae commonly causes respiratory tract infections in children, and epidemiological investigations strongly link infection to the pathogenesis of asthma. The immune system in early life is immature and may not respond appropriately to pathogens. Toll-like receptor (TLR)2 and 4 are reg...

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Autores principales: Emma L Beckett, Simon Phipps, Malcolm R Starkey, Jay C Horvat, Kenneth W Beagley, Paul S Foster, Philip M Hansbro
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/6e7a5439e92d4b5eb40830deb1371fc3
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