Bunyaviridae RNA polymerases (L-protein) have an N-terminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription.
Bunyaviruses are a large family of segmented RNA viruses which, like influenza virus, use a cap-snatching mechanism for transcription whereby short capped primers derived by endonucleolytic cleavage of host mRNAs are used by the viral RNA-dependent RNA polymerase (L-protein) to transcribe viral mRNA...
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Main Authors: | Juan Reguera, Friedemann Weber, Stephen Cusack |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Subjects: | |
Online Access: | https://doaj.org/article/6e7d5a3c8d1d400a834e726757968f7a |
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