Bunyaviridae RNA polymerases (L-protein) have an N-terminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription.
Bunyaviruses are a large family of segmented RNA viruses which, like influenza virus, use a cap-snatching mechanism for transcription whereby short capped primers derived by endonucleolytic cleavage of host mRNAs are used by the viral RNA-dependent RNA polymerase (L-protein) to transcribe viral mRNA...
Enregistré dans:
Auteurs principaux: | Juan Reguera, Friedemann Weber, Stephen Cusack |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2010
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/6e7d5a3c8d1d400a834e726757968f7a |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription.
par: Benjamin Morin, et autres
Publié: (2010) -
Structural analysis of specific metal chelating inhibitor binding to the endonuclease domain of influenza pH1N1 (2009) polymerase.
par: Eva Kowalinski, et autres
Publié: (2012) -
Mechanism of RNA polymerase III termination-associated reinitiation-recycling conferred by the essential function of the N terminal-and-linker domain of the C11 subunit
par: Saurabh Mishra, et autres
Publié: (2021) -
Extracellular cap domain is an essential component of the TRPV1 gating mechanism
par: Kirill D. Nadezhdin, et autres
Publié: (2021) -
Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain
par: Bede Portz, et autres
Publié: (2017)