A glycoside analog of mammalian oligomannose formulated with a TLR4-stimulating adjuvant elicits HIV-1 cross-reactive antibodies
Abstract The occurrence of oligomannose-specific broadly neutralizing antibodies (bnAbs) has spurred efforts to develop immunogens that can elicit similar antibodies. Here, we report on the antigenicity and immunogenicity of a CRM197-conjugate of a previously reported oligomannose mimetic. Oligomann...
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Autores principales: | Jean-François Bruxelle, Tess Kirilenko, Nino Trattnig, Yiqiu Yang, Matteo Cattin, Paul Kosma, Ralph Pantophlet |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/6e82ed37f9564815b8027762ff199af6 |
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