<i>STK11/LKB1</i> Modulation of the Immune Response in Lung Cancer: From Biology to Therapeutic Impact

Código QR

<i>STK11/LKB1</i> Modulation of the Immune Response in Lung Cancer: From Biology to Therapeutic Impact

The <i>STK11/LKB1</i> gene codes for liver kinase B1 (<i>STK11/LKB1</i>), a highly conserved serine/threonine kinase involved in many energy-related cellular processes. The canonical tumor-suppressive role for <i>STK11/LKB1</i> involves the activation of AMPK-rela...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Elvire Pons-Tostivint, Alexandre Lugat, Jean-François Fontenau, Marc Guillaume Denis, Jaafar Bennouna
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	<i>STK11/LKB1</i> non-small cell lung cancer immunotherapy biomarker KRAS Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/6e838efed2924f16aa464fddfa4762ff
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

EVT‐701 is a novel selective and safe mitochondrial complex 1 inhibitor with potent anti‐tumor activity in models of solid cancers
por: Raquel Luna Yolba, et al.
Publicado: (2021)

Associations of Polymorphisms Localized in the 3′UTR Regions of the <i>KRAS</i>, <i>NRAS</i>, <i>MAPK1</i> Genes with Laryngeal Squamous Cell Carcinoma
por: Ruta Insodaite, et al.
Publicado: (2021)

m<sup>6</sup>A mRNA Methylation Regulates LKB1 to Promote Autophagy of Hepatoblastoma Cells through Upregulated Phosphorylation of AMPK
por: Guohui Li, et al.
Publicado: (2021)

FLO11, a Developmental Gene Conferring Impressive Adaptive Plasticity to the Yeast <i>Saccharomyces cerevisiae</i>
por: Clara Bouyx, et al.
Publicado: (2021)

STK3 promotes gastric carcinogenesis by activating Ras-MAPK mediated cell cycle progression and serves as an independent prognostic biomarker
por: Bonan Chen, et al.
Publicado: (2021)

Tick Cell Culture Analysis of Growth Dynamics and Cellular Tropism of <i>Rickettsia buchneri</i>, an Endosymbiont of the Blacklegged Tick, <i>Ixodes scapularis</i>
por: Cody J. Thorpe, et al.
Publicado: (2021)

Highlights of Immunomodulation in <i>Salmonella</i>-Based Cancer Therapy
por: Christian R. Pangilinan, et al.
Publicado: (2021)

Survival of Enterohemorrhagic <i>Escherichia coli</i> O104:H4 Strain C227/11Φcu in Agricultural Soils Depends on <i>rpoS</i> and Environmental Factors
por: Katharina Detert, et al.
Publicado: (2021)

A Novel Spo11 Homologue Functions as a Positive Regulator in Cyst Differentiation in <i>Giardia lamblia</i>
por: Yu-Chien Chen, et al.
Publicado: (2021)

Pathogenic <i>BRCA</i> Variants as Biomarkers for Risk in Prostate Cancer
por: Ciara S. McNevin, et al.
Publicado: (2021)

Development of a Multiplex Droplet Digital PCR Assay for the Detection of <i>Babesia</i>, <i>Bartonella</i>, and <i>Borrelia</i> Species
por: Ricardo Maggi, et al.
Publicado: (2021)

The Role of <i>Pseudomonas aeruginosa</i> Virulence Factors in Cytoskeletal Dysregulation and Lung Barrier Dysfunction
por: Brant M. Wagener, et al.
Publicado: (2021)

Effect of Gamma Irradiation on Enhanced Biological Activities of Exopolysaccharide from <i>Halomonas desertis</i> G11: Biochemical and Genomic Insights
por: Habib Chouchane, et al.
Publicado: (2021)

(<i>L</i>,⊙)-Fuzzy (<i>K</i>,<i>E</i>)-Soft Filter
por: Ahmed Aref Abd El-Latif, et al.
Publicado: (2021)

Knockout of the <i>hsd11b2</i> Gene Extends the Cortisol Stress Response in Both Zebrafish Larvae and Adults
por: Antonia Theodoridi, et al.
Publicado: (2021)

Comparison of the Scorpionism Caused by <i>Centruroides</i> <i>margaritatus</i>, <i>Tityus</i> <i>pachyurus</i> and <i>Tityus</i> n. sp. aff. <i>metuendus</i> Scorpion Venoms in Colombia
por: Leydy Lorena Mendoza-Tobar, et al.
Publicado: (2021)

<i>C</i>*-Algebra Valued Modular <i>G</i>-Metric Spaces with Applications in Fixed Point Theory
por: Dipankar Das, et al.
Publicado: (2021)

The Effects of <i>Aspergillus fumigatus</i> Colonization on Lung Function in Patients with Cystic Fibrosis
por: Mahasin Al Shakirchi, et al.
Publicado: (2021)

A Journey from June 2018 to October 2021 with <i>N</i>,<i>N</i>-Dimethylformamide and <i>N</i>,<i>N</i>-Dimethylacetamide as Reactants
por: Jacques Muzart
Publicado: (2021)

Changes in the Sensitization Pattern to <i>Alternaria alternata</i> Allergens in Patients Treated with Alt a 1 Immunotherapy
por: David Rodríguez, et al.
Publicado: (2021)

<i>f</i>(<i>T</i>, <i>B</i>) Cosmography for High Redshifts
por: Celia Escamilla-Rivera, et al.
Publicado: (2021)

Seaweed Extract-Stimulated Priming in <i>Arabidopsis thaliana</i> and <i>Solanum lycopersicum</i>
por: Md Tohidul Islam, et al.
Publicado: (2021)

Separate Fractional (<i>p</i>,<i>q</i>)-Integrodifference Equations via Nonlocal Fractional (<i>p</i>,<i>q</i>)-Integral Boundary Conditions
por: Thongchai Dumrongpokaphan, et al.
Publicado: (2021)

Development of Various <i>Leishmania</i> (<i>Sauroleishmania</i>) <i>tarentolae</i> Strains in Three <i>Phlebotomus</i> Species
por: Lucie Ticha, et al.
Publicado: (2021)

Mycosubtilin Produced by <i>Bacillus subtilis</i> ATCC6633 Inhibits Growth and Mycotoxin Biosynthesis of <i>Fusarium graminearum</i> and <i>Fusarium verticillioides</i>
por: Chenjie Yu, et al.
Publicado: (2021)

The New Human <i>Babesia</i> sp. FR1 Is a European Member of the <i>Babesia</i> sp. MO1 Clade
por: Claire Bonsergent, et al.
Publicado: (2021)

Region-Specific Biomarkers and Their Mechanisms in the Treatment of Lung Adenocarcinoma: A Study of <i>Panax quinquefolius</i> from Wendeng, China
por: Xuanming Zhang, et al.
Publicado: (2021)

Role of <i>Sesamia nonagrioides</i> and <i>Ostrinia nubilalis</i> as Vectors of <i>Fusarium</i> spp. and Contribution of Corn Borer-Resistant Bt Maize to Mycotoxin Reduction
por: María Arias-Martín, et al.
Publicado: (2021)

<i>k</i>-Zero-Divisor and Ideal-Based <i>k</i>-Zero-Divisor Hypergraphs of Some Commutative Rings
por: Pinkaew Siriwong, et al.
Publicado: (2021)

KRAS and NRAS genes mutations as biomarkers in the therapy of colorectal cancer and the basic methods of their detection
por: Olga I. Brovkina, et al.
Publicado: (2021)

Expression Patterns of miR398, miR167, and miR159 in the Interaction between Bread Wheat (<i>Triticum</i> <i>aestivum</i> L.) and Pathogenic <i>Fusarium</i> <i>culmorum</i> and Beneficial <i>Trichoderma</i> Fungi
por: Sylwia Salamon, et al.
Publicado: (2021)

Establishment of a Novel and Efficient <i>Agrobacterium</i>-Mediated <i>in Planta</i> Transformation System for Passion Fruit (<i>Passiflora edulis</i>)
por: Hafiz Muhammad Rizwan, et al.
Publicado: (2021)

Production of Genistein in <i>Amaranthus tricolor</i> var. <i>tristis</i> and <i>Spinacia oleracea</i> by Expression of <i>Glycine max Isoflavone Synthase</i>
por: Ashwini Malla, et al.
Publicado: (2021)

Removal of Flotation Collector <i>O</i>-Isopropyl-<i>N</i>-ethylthionocarbamate from Wastewater
por: Zhe Wang, et al.
Publicado: (2021)

Mycorrhizal Compatibility and Germination-Promoting Activity of <i>Tulasnella</i> Species in Two Species of Orchid (<i>Cymbidium mannii</i> and <i>Epidendrum radicans</i>)
por: Qianyu Yang, et al.
Publicado: (2021)

Flavonoids Accumulation in Fruit Peel and Expression Profiling of Related Genes in Purple (<i>Passiflora edulis</i> f. <i>edulis</i>) and Yellow (<i>Passiflora edulis</i> f. <i>flavicarpa</i>) Passion Fruits
por: Meng Shi, et al.
Publicado: (2021)

Development of a Multiplex Loop-Mediated Isothermal Amplification Assay for Diagnosis of <i>Plasmodium</i> spp., <i>Plasmodium falciparum</i> and <i>Plasmodium vivax</i>
por: Woong Sik Jang, et al.
Publicado: (2021)

Emergence of Methicillin-Resistant <i>Staphylococcus aureus</i> ST239/241 <i>SCCmec</i>-III Mercury in Eastern Algeria
por: Hanane Aouati, et al.
Publicado: (2021)

On the Fekete–Szegö Problem for Meromorphic Functions Associated with <i>p</i>,<i>q</i>-Wright Type Hypergeometric Function
por: Adriana Cătaş
Publicado: (2021)

Isolation of the Novel Phage PHB09 and Its Potential Use against the Plant Pathogen <i>Pseudomonas syringae</i> pv. <i>actinidiae</i>
por: Yanxi Liu, et al.
Publicado: (2021)