Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor

Human cytomegalovirus (HCMV) can persist for the life of a host in the face of robust immune responses owing to a wide range of immune evasion strategies. Here Liu and colleagues show that HCMV evades the IgG-mediated response by the endoplasmic reticulum-associated degradation of the neonatal Fc re...

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Autores principales:	Xiaoyang Liu, Senthilkumar Palaniyandi, Iowis Zhu, Jin Tang, Weizhong Li, Xiaoling Wu, Susan Park Ochsner, C. David Pauza, Jeffrey I. Cohen, Xiaoping Zhu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6e85368b58fb47d9aed9931f8276b0ca
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spelling	oai:doaj.org-article:6e85368b58fb47d9aed9931f8276b0ca2021-12-02T16:58:19ZHuman cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor10.1038/s41467-019-10865-y2041-1723https://doaj.org/article/6e85368b58fb47d9aed9931f8276b0ca2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10865-yhttps://doaj.org/toc/2041-1723Human cytomegalovirus (HCMV) can persist for the life of a host in the face of robust immune responses owing to a wide range of immune evasion strategies. Here Liu and colleagues show that HCMV evades the IgG-mediated response by the endoplasmic reticulum-associated degradation of the neonatal Fc receptor for IgG.Xiaoyang LiuSenthilkumar PalaniyandiIowis ZhuJin TangWeizhong LiXiaoling WuSusan Park OchsnerC. David PauzaJeffrey I. CohenXiaoping ZhuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaoyang Liu Senthilkumar Palaniyandi Iowis Zhu Jin Tang Weizhong Li Xiaoling Wu Susan Park Ochsner C. David Pauza Jeffrey I. Cohen Xiaoping Zhu Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor
description	Human cytomegalovirus (HCMV) can persist for the life of a host in the face of robust immune responses owing to a wide range of immune evasion strategies. Here Liu and colleagues show that HCMV evades the IgG-mediated response by the endoplasmic reticulum-associated degradation of the neonatal Fc receptor for IgG.
format	article
author	Xiaoyang Liu Senthilkumar Palaniyandi Iowis Zhu Jin Tang Weizhong Li Xiaoling Wu Susan Park Ochsner C. David Pauza Jeffrey I. Cohen Xiaoping Zhu
author_facet	Xiaoyang Liu Senthilkumar Palaniyandi Iowis Zhu Jin Tang Weizhong Li Xiaoling Wu Susan Park Ochsner C. David Pauza Jeffrey I. Cohen Xiaoping Zhu
author_sort	Xiaoyang Liu
title	Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor
title_short	Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor
title_full	Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor
title_fullStr	Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor
title_full_unstemmed	Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor
title_sort	human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the fcrn receptor
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/6e85368b58fb47d9aed9931f8276b0ca
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Human cytomegalovirus evades antibody-mediated immunity through endoplasmic reticulum-associated degradation of the FcRn receptor

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