Role and Function of O-GlcNAcylation in Cancer

Cancer cells are able to reprogram their glucose metabolism and retain energy via glycolysis even under aerobic conditions. They activate the hexosamine biosynthetic pathway (HBP), and the complex interplay of O-linked N-acetylglucosaminylation (O-GlcNAcylation) via deprivation of nutrients or incre...

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Bibliographic Details
Main Authors: Jii Bum Lee, Kyoung-Ho Pyo, Hye Ryun Kim
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
Online Access:https://doaj.org/article/6e8bd2548de24ebea13a9ecd381bb1cf
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