Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation

Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation

Necrotizing enterocolitis (NEC) is one of the most lethal gastrointestinal emergencies in neonates needing precision treatment. Here the authors show that remote ischemic conditioning is a non-invasive therapeutic method that enhances blood flow in the intestine, reduces damage, and improves NEC out...

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Autores principales: Yuhki Koike, Bo Li, Niloofar Ganji, Haitao Zhu, Hiromu Miyake, Yong Chen, Carol Lee, Maarten Janssen Lok, Carlos Zozaya, Ethan Lau, Dorothy Lee, Sinobol Chusilp, Zhen Zhang, Masaya Yamoto, Richard Y. Wu, Mikihiro Inoue, Keiichi Uchida, Masato Kusunoki, Paul Delgado-Olguin, Luc Mertens, Alan Daneman, Simon Eaton, Philip M. Sherman, Agostino Pierro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/6e92e63bc1ea47cd9e3d5b8b7748b3ba
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spelling oai:doaj.org-article:6e92e63bc1ea47cd9e3d5b8b7748b3ba2021-12-02T17:37:14ZRemote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation10.1038/s41467-020-18750-92041-1723https://doaj.org/article/6e92e63bc1ea47cd9e3d5b8b7748b3ba2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18750-9https://doaj.org/toc/2041-1723Necrotizing enterocolitis (NEC) is one of the most lethal gastrointestinal emergencies in neonates needing precision treatment. Here the authors show that remote ischemic conditioning is a non-invasive therapeutic method that enhances blood flow in the intestine, reduces damage, and improves NEC outcome.Yuhki KoikeBo LiNiloofar GanjiHaitao ZhuHiromu MiyakeYong ChenCarol LeeMaarten Janssen LokCarlos ZozayaEthan LauDorothy LeeSinobol ChusilpZhen ZhangMasaya YamotoRichard Y. WuMikihiro InoueKeiichi UchidaMasato KusunokiPaul Delgado-OlguinLuc MertensAlan DanemanSimon EatonPhilip M. ShermanAgostino PierroNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yuhki Koike
Bo Li
Niloofar Ganji
Haitao Zhu
Hiromu Miyake
Yong Chen
Carol Lee
Maarten Janssen Lok
Carlos Zozaya
Ethan Lau
Dorothy Lee
Sinobol Chusilp
Zhen Zhang
Masaya Yamoto
Richard Y. Wu
Mikihiro Inoue
Keiichi Uchida
Masato Kusunoki
Paul Delgado-Olguin
Luc Mertens
Alan Daneman
Simon Eaton
Philip M. Sherman
Agostino Pierro
Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation
description Necrotizing enterocolitis (NEC) is one of the most lethal gastrointestinal emergencies in neonates needing precision treatment. Here the authors show that remote ischemic conditioning is a non-invasive therapeutic method that enhances blood flow in the intestine, reduces damage, and improves NEC outcome.
format article
author Yuhki Koike
Bo Li
Niloofar Ganji
Haitao Zhu
Hiromu Miyake
Yong Chen
Carol Lee
Maarten Janssen Lok
Carlos Zozaya
Ethan Lau
Dorothy Lee
Sinobol Chusilp
Zhen Zhang
Masaya Yamoto
Richard Y. Wu
Mikihiro Inoue
Keiichi Uchida
Masato Kusunoki
Paul Delgado-Olguin
Luc Mertens
Alan Daneman
Simon Eaton
Philip M. Sherman
Agostino Pierro
author_facet Yuhki Koike
Bo Li
Niloofar Ganji
Haitao Zhu
Hiromu Miyake
Yong Chen
Carol Lee
Maarten Janssen Lok
Carlos Zozaya
Ethan Lau
Dorothy Lee
Sinobol Chusilp
Zhen Zhang
Masaya Yamoto
Richard Y. Wu
Mikihiro Inoue
Keiichi Uchida
Masato Kusunoki
Paul Delgado-Olguin
Luc Mertens
Alan Daneman
Simon Eaton
Philip M. Sherman
Agostino Pierro
author_sort Yuhki Koike
title Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation
title_short Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation
title_full Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation
title_fullStr Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation
title_full_unstemmed Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation
title_sort remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/6e92e63bc1ea47cd9e3d5b8b7748b3ba
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