A Review of <i>Rhazya stricta</i> Decne Phytochemistry, Bioactivities, Pharmacological Activities, Toxicity, and Folkloric Medicinal Uses

The local medicinal plant <i>Rhazya stricta Decne</i> is reviewed for its folkloric medicinal, phytochemical, pharmacological, biological, and toxicological features. <i>R. stricta</i> has been used widely in different cultures for various medical disorders. The phytochemical...

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Autores principales: Abdulaziz Albeshri, Nabih A. Baeshen, Thamer A. Bouback, Abdullah A. Aljaddawi
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/6e9fd0845422411d8fa747e46ceb0a23
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Sumario:The local medicinal plant <i>Rhazya stricta Decne</i> is reviewed for its folkloric medicinal, phytochemical, pharmacological, biological, and toxicological features. <i>R. stricta</i> has been used widely in different cultures for various medical disorders. The phytochemical studies performed on the <i>R. stricta</i> extract revealed many alkaloidal and fatty acid compounds. Moreover, several flavonoid and terpenoid compounds were also detected. Pharmacological activates of <i>R. stricta</i> extracts are approved to possess antimicrobial, antioxidant, anticancer, antidiabetic, and antihypertensive activities. Additionally, <i>R. stricta</i> extract was found to hold biological activates such as larvicidal and phytoremediation activates <i>R. stricta</i> extract was found to be toxic, genotoxic, and mutagenic. <i>R. stricta</i> contains novel phytochemical compounds that have not been investigated pharmacologically. Further research is needed through in vitro and in vivo experiments to pave the road for these compounds for medical, veterinary, and ecological uses.