A new phenothiazine derivate is active against Clostridioides difficile and shows low cytotoxicity.

The rapid evolution of antibiotic resistance in Clostridioides difficile and the consequent effects on prevention and treatment of C. difficile infections (CDIs) are matters of concern for public health. Thioridazine, a compound belonging to the phenothiazine group, has previous shown antimicrobial...

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Autores principales: Troels Ronco, Francisca Maria Aragao, Lasse Saaby, Jørn B Christensen, Anders Permin, Andrew R Williams, Stig M Thamsborg, Rikke H Olsen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/6ea30fd443644510893431c84e425e63
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