Catalytic enantioselective construction of axial chirality in 1,3-disubstituted allenes
Highly enantioselective synthesis of allenes has been relying, so far, on the steric hindrance of substrates. Here the authors achieve excellent stereocontrol in the synthesis of chiral allenes with a palladium-DTBM-SEGPHOS catalytic system in a non-substrate-dependent manner.
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2019
|
| Subjects: | |
| Online Access: | https://doaj.org/article/6ea835ae1b0b4f5f95dfba7ff6028b31 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|