Brain-derived neurotrophic factor/FK506-binding protein 5 genotype by childhood trauma interactions do not impact on hippocampal volume and cognitive performance.

Brain-derived neurotrophic factor/FK506-binding protein 5 genotype by childhood trauma interactions do not impact on hippocampal volume and cognitive performance.

In the development of psychotic symptoms, environmental and genetic factors may both play a role. The reported association between childhood trauma and psychotic symptoms could therefore be moderated by single nucleotide polymorphisms (SNPs) associated with the stress response, such as FK506-binding...

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Autores principales: Dennis Hernaus, Ruud van Winkel, Ed Gronenschild, Petra Habets, Gunter Kenis, Machteld Marcelis, Jim van Os, Inez Myin-Germeys, Dina Collip, for Genetic Risk and Outcome in Psychosis (G.R.O.U.P.)
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6ebe141b3af841afac850883f1fe142d
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