Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action
Lantibiotics are ribosomally synthesized and posttranslationally modified peptide antibiotics. Although the membrane-associated lantibiotic biosynthesis machinery has long been proposed to exist, the isolation of such a complex has not been reported yet, which limits the elucidation of the processi...
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American Society for Microbiology
2021
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oai:doaj.org-article:6ece06b81b5b4483909e02ffc02780df2021-11-03T21:52:35ZIsolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action2150-751110.1128/mBio.02585-21https://doaj.org/article/6ece06b81b5b4483909e02ffc02780df2021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02585-21https://doaj.org/toc/2150-7511 Lantibiotics are ribosomally synthesized and posttranslationally modified peptide antibiotics. Although the membrane-associated lantibiotic biosynthesis machinery has long been proposed to exist, the isolation of such a complex has not been reported yet, which limits the elucidation of the processive mechanism of lantibiotic biosynthesis.Jingqi ChenOscar P. KuipersAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021) |
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DOAJ |
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EN |
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Microbiology QR1-502 |
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Microbiology QR1-502 Jingqi Chen Oscar P. Kuipers Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action |
description |
Lantibiotics are ribosomally synthesized and posttranslationally modified peptide antibiotics. Although the membrane-associated lantibiotic biosynthesis machinery has long been proposed to exist, the isolation of such a complex has not been reported yet, which limits the elucidation of the processive mechanism of lantibiotic biosynthesis. |
format |
article |
author |
Jingqi Chen Oscar P. Kuipers |
author_facet |
Jingqi Chen Oscar P. Kuipers |
author_sort |
Jingqi Chen |
title |
Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action |
title_short |
Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action |
title_full |
Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action |
title_fullStr |
Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action |
title_full_unstemmed |
Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action |
title_sort |
isolation and analysis of the nisin biosynthesis complex nisbtc: further insights into their cooperative action |
publisher |
American Society for Microbiology |
publishDate |
2021 |
url |
https://doaj.org/article/6ece06b81b5b4483909e02ffc02780df |
work_keys_str_mv |
AT jingqichen isolationandanalysisofthenisinbiosynthesiscomplexnisbtcfurtherinsightsintotheircooperativeaction AT oscarpkuipers isolationandanalysisofthenisinbiosynthesiscomplexnisbtcfurtherinsightsintotheircooperativeaction |
_version_ |
1718445403303575552 |