Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action

Lantibiotics are ribosomally synthesized and posttranslationally modified peptide antibiotics. Although the membrane-associated lantibiotic biosynthesis machinery has long been proposed to exist, the isolation of such a complex has not been reported yet, which limits the elucidation of the processi...

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Autores principales: Jingqi Chen, Oscar P. Kuipers
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Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/6ece06b81b5b4483909e02ffc02780df
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spelling oai:doaj.org-article:6ece06b81b5b4483909e02ffc02780df2021-11-03T21:52:35ZIsolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action2150-751110.1128/mBio.02585-21https://doaj.org/article/6ece06b81b5b4483909e02ffc02780df2021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.02585-21https://doaj.org/toc/2150-7511 Lantibiotics are ribosomally synthesized and posttranslationally modified peptide antibiotics. Although the membrane-associated lantibiotic biosynthesis machinery has long been proposed to exist, the isolation of such a complex has not been reported yet, which limits the elucidation of the processive mechanism of lantibiotic biosynthesis.Jingqi ChenOscar P. KuipersAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Jingqi Chen
Oscar P. Kuipers
Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action
description Lantibiotics are ribosomally synthesized and posttranslationally modified peptide antibiotics. Although the membrane-associated lantibiotic biosynthesis machinery has long been proposed to exist, the isolation of such a complex has not been reported yet, which limits the elucidation of the processive mechanism of lantibiotic biosynthesis.
format article
author Jingqi Chen
Oscar P. Kuipers
author_facet Jingqi Chen
Oscar P. Kuipers
author_sort Jingqi Chen
title Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action
title_short Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action
title_full Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action
title_fullStr Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action
title_full_unstemmed Isolation and Analysis of the Nisin Biosynthesis Complex NisBTC: further Insights into Their Cooperative Action
title_sort isolation and analysis of the nisin biosynthesis complex nisbtc: further insights into their cooperative action
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/6ece06b81b5b4483909e02ffc02780df
work_keys_str_mv AT jingqichen isolationandanalysisofthenisinbiosynthesiscomplexnisbtcfurtherinsightsintotheircooperativeaction
AT oscarpkuipers isolationandanalysisofthenisinbiosynthesiscomplexnisbtcfurtherinsightsintotheircooperativeaction
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