Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing

Here the authors use optogenetic tools to directly measure spatial signal processing in leukocyte chemotaxis. Their results reveal the importance of multiple negative feedback loops for maintaining spatial information in chemotaxis.

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Autores principales:	George R. R. Bell, Esther Rincón, Emel Akdoğan, Sean R. Collins
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6ece3c5855d54a95807d677d7e95147c
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spelling	oai:doaj.org-article:6ece3c5855d54a95807d677d7e95147c2021-11-21T12:35:42ZOptogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing10.1038/s41467-021-26371-z2041-1723https://doaj.org/article/6ece3c5855d54a95807d677d7e95147c2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26371-zhttps://doaj.org/toc/2041-1723Here the authors use optogenetic tools to directly measure spatial signal processing in leukocyte chemotaxis. Their results reveal the importance of multiple negative feedback loops for maintaining spatial information in chemotaxis.George R. R. BellEsther RincónEmel AkdoğanSean R. CollinsNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q George R. R. Bell Esther Rincón Emel Akdoğan Sean R. Collins Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing
description	Here the authors use optogenetic tools to directly measure spatial signal processing in leukocyte chemotaxis. Their results reveal the importance of multiple negative feedback loops for maintaining spatial information in chemotaxis.
format	article
author	George R. R. Bell Esther Rincón Emel Akdoğan Sean R. Collins
author_facet	George R. R. Bell Esther Rincón Emel Akdoğan Sean R. Collins
author_sort	George R. R. Bell
title	Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing
title_short	Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing
title_full	Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing
title_fullStr	Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing
title_full_unstemmed	Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing
title_sort	optogenetic control of receptors reveals distinct roles for actin- and cdc42-dependent negative signals in chemotactic signal processing
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6ece3c5855d54a95807d677d7e95147c
work_keys_str_mv	AT georgerrbell optogeneticcontrolofreceptorsrevealsdistinctrolesforactinandcdc42dependentnegativesignalsinchemotacticsignalprocessing AT estherrincon optogeneticcontrolofreceptorsrevealsdistinctrolesforactinandcdc42dependentnegativesignalsinchemotacticsignalprocessing AT emelakdogan optogeneticcontrolofreceptorsrevealsdistinctrolesforactinandcdc42dependentnegativesignalsinchemotacticsignalprocessing AT seanrcollins optogeneticcontrolofreceptorsrevealsdistinctrolesforactinandcdc42dependentnegativesignalsinchemotacticsignalprocessing
_version_	1718418889301295104

Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing

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