Ribavirin exerts differential effects on functions of Cd4+ Th1, Th2, and regulatory T cell clones in hepatitis C.

Ribavirin improves outcomes of therapy in chronic hepatitis C but its mode of action has still remained unclear. Since ribavirin has been proposed to modulate the host's T cell responses, we studied its direct effects on CD4(+) T cell clones with diverse functional polarization which had been g...

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Autores principales: Bettina Langhans, Hans Dieter Nischalke, Simone Arndt, Ingrid Braunschweiger, Jacob Nattermann, Tilman Sauerbruch, Ulrich Spengler
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/6ed806fc93364a7b898e0604559ef335
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