Efficient human breast cancer xenograft regression after a single treatment with a novel liposomal formulation of epirubicin prepared using the EDTA ion gradient method.

Efficient human breast cancer xenograft regression after a single treatment with a novel liposomal formulation of epirubicin prepared using the EDTA ion gradient method.

Liposomes act as efficient drug carriers. Recently, epirubicin (EPI) formulation was developed using a novel EDTA ion gradient method for drug encapsulation. This formulation displayed very good stability and drug retention in vitro in a two-year long-term stability experiment. The cryo-TEM images s...

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Autores principales: Jerzy Gubernator, Dominik Lipka, Mariola Korycińska, Katarzyna Kempińska, Magdalena Milczarek, Joanna Wietrzyk, Rafał Hrynyk, Sabine Barnert, Regine Süss, Arkadiusz Kozubek
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6ed88cd774154c58842be34e310f3b09
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