Meta-regression of randomized control trials with antithrombotics: weak correlation between net clinical benefit and all cause-mortality

Abstract This study aimed to explore the validity of the use of the net clinical benefit (NCB), i.e. the sum of major bleeding and thrombotic events, as a potential surrogate for all-cause mortality in clinical trials assessing antithrombotics. Published randomized controlled trials testing anticoag...

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Autores principales: Roubi Kilo, Silvy Laporte, Rama Arab, Sabine Mainbourg, Steeve Provencher, Guillaume Grenet, Laurent Bertoletti, Laurent Villeneuve, Michel Cucherat, Jean-Christophe Lega, META-EMBOL Group
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6ede1d7ffd7e45c089cbac448dc01abd
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