A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius

Certain archaea appear to metabolize fatty acids, but the regulation of these pathways is unclear. Here, Wang et al. provide genetic, functional and structural evidence supporting that a TetR-family transcriptional regulator is involved in regulation of fatty acid metabolism in Sulfolobus acidocalda...

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Autores principales: Kun Wang, David Sybers, Hassan Ramadan Maklad, Liesbeth Lemmens, Charlotte Lewyllie, Xiaoxiao Zhou, Frank Schult, Christopher Bräsen, Bettina Siebers, Karin Valegård, Ann-Christin Lindås, Eveline Peeters
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/6ee26d80636d401a89021bf702b0c0c3
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Sumario:Certain archaea appear to metabolize fatty acids, but the regulation of these pathways is unclear. Here, Wang et al. provide genetic, functional and structural evidence supporting that a TetR-family transcriptional regulator is involved in regulation of fatty acid metabolism in Sulfolobus acidocaldarius.