A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius

Certain archaea appear to metabolize fatty acids, but the regulation of these pathways is unclear. Here, Wang et al. provide genetic, functional and structural evidence supporting that a TetR-family transcriptional regulator is involved in regulation of fatty acid metabolism in Sulfolobus acidocalda...

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Autores principales: Kun Wang, David Sybers, Hassan Ramadan Maklad, Liesbeth Lemmens, Charlotte Lewyllie, Xiaoxiao Zhou, Frank Schult, Christopher Bräsen, Bettina Siebers, Karin Valegård, Ann-Christin Lindås, Eveline Peeters
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/6ee26d80636d401a89021bf702b0c0c3
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spelling oai:doaj.org-article:6ee26d80636d401a89021bf702b0c0c32021-12-02T14:38:57ZA TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius10.1038/s41467-019-09479-12041-1723https://doaj.org/article/6ee26d80636d401a89021bf702b0c0c32019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09479-1https://doaj.org/toc/2041-1723Certain archaea appear to metabolize fatty acids, but the regulation of these pathways is unclear. Here, Wang et al. provide genetic, functional and structural evidence supporting that a TetR-family transcriptional regulator is involved in regulation of fatty acid metabolism in Sulfolobus acidocaldarius.Kun WangDavid SybersHassan Ramadan MakladLiesbeth LemmensCharlotte LewyllieXiaoxiao ZhouFrank SchultChristopher BräsenBettina SiebersKarin ValegårdAnn-Christin LindåsEveline PeetersNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kun Wang
David Sybers
Hassan Ramadan Maklad
Liesbeth Lemmens
Charlotte Lewyllie
Xiaoxiao Zhou
Frank Schult
Christopher Bräsen
Bettina Siebers
Karin Valegård
Ann-Christin Lindås
Eveline Peeters
A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius
description Certain archaea appear to metabolize fatty acids, but the regulation of these pathways is unclear. Here, Wang et al. provide genetic, functional and structural evidence supporting that a TetR-family transcriptional regulator is involved in regulation of fatty acid metabolism in Sulfolobus acidocaldarius.
format article
author Kun Wang
David Sybers
Hassan Ramadan Maklad
Liesbeth Lemmens
Charlotte Lewyllie
Xiaoxiao Zhou
Frank Schult
Christopher Bräsen
Bettina Siebers
Karin Valegård
Ann-Christin Lindås
Eveline Peeters
author_facet Kun Wang
David Sybers
Hassan Ramadan Maklad
Liesbeth Lemmens
Charlotte Lewyllie
Xiaoxiao Zhou
Frank Schult
Christopher Bräsen
Bettina Siebers
Karin Valegård
Ann-Christin Lindås
Eveline Peeters
author_sort Kun Wang
title A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius
title_short A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius
title_full A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius
title_fullStr A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius
title_full_unstemmed A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius
title_sort tetr-family transcription factor regulates fatty acid metabolism in the archaeal model organism sulfolobus acidocaldarius
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/6ee26d80636d401a89021bf702b0c0c3
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