A novel cystathionine γ-lyase inhibitor, I194496, inhibits the growth and metastasis of human TNBC via downregulating multiple signaling pathways

Abstract Triple-negative breast cancer (TNBC) is a high-risk subtype of breast cancer with high capacity for metastasis and lacking of therapeutic targets. Our previous studies indicated that cystathionine γ-lyase (CSE) may be a new target related to the recurrence or metastasis of TNBC. Downregulat...

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Autores principales: Ya Liu, Lupeng Wang, Xiuli Zhang, Yuying Deng, Limin Pan, Hui Li, Xiaoyan Shi, Tianxiao Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6ee730420102402986db3c8ac9a8330d
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