A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates

Mechanisms coupling Hox genes to neural crest are largely unknown. Here, the authors use cross species regulatory comparisons between the Hox2 genes of jawed vertebrates and lamprey, a jawless vertebrate, finding a conserved ancestral mechanism for Hox2 neural crest regulation.

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Autores principales:	Hugo J. Parker, Bony De Kumar, Stephen A. Green, Karin D. Prummel, Christopher Hess, Charles K. Kaufman, Christian Mosimann, Leanne M. Wiedemann, Marianne E. Bronner, Robb Krumlauf
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6ef1bae99a3745869c82f9964c185540
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spelling	oai:doaj.org-article:6ef1bae99a3745869c82f9964c1855402021-12-02T15:36:04ZA Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates10.1038/s41467-019-09197-82041-1723https://doaj.org/article/6ef1bae99a3745869c82f9964c1855402019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09197-8https://doaj.org/toc/2041-1723Mechanisms coupling Hox genes to neural crest are largely unknown. Here, the authors use cross species regulatory comparisons between the Hox2 genes of jawed vertebrates and lamprey, a jawless vertebrate, finding a conserved ancestral mechanism for Hox2 neural crest regulation.Hugo J. ParkerBony De KumarStephen A. GreenKarin D. PrummelChristopher HessCharles K. KaufmanChristian MosimannLeanne M. WiedemannMarianne E. BronnerRobb KrumlaufNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hugo J. Parker Bony De Kumar Stephen A. Green Karin D. Prummel Christopher Hess Charles K. Kaufman Christian Mosimann Leanne M. Wiedemann Marianne E. Bronner Robb Krumlauf A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates
description	Mechanisms coupling Hox genes to neural crest are largely unknown. Here, the authors use cross species regulatory comparisons between the Hox2 genes of jawed vertebrates and lamprey, a jawless vertebrate, finding a conserved ancestral mechanism for Hox2 neural crest regulation.
format	article
author	Hugo J. Parker Bony De Kumar Stephen A. Green Karin D. Prummel Christopher Hess Charles K. Kaufman Christian Mosimann Leanne M. Wiedemann Marianne E. Bronner Robb Krumlauf
author_facet	Hugo J. Parker Bony De Kumar Stephen A. Green Karin D. Prummel Christopher Hess Charles K. Kaufman Christian Mosimann Leanne M. Wiedemann Marianne E. Bronner Robb Krumlauf
author_sort	Hugo J. Parker
title	A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates
title_short	A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates
title_full	A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates
title_fullStr	A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates
title_full_unstemmed	A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates
title_sort	hox-tale regulatory circuit for neural crest patterning is conserved across vertebrates
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/6ef1bae99a3745869c82f9964c185540
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A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates

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