Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy

The evolutionary progression from primary to metastatic prostate cancer is largely uncharted, and the implications for liquid biopsy are unexplored. Here, the authors use deep genomic sequencing and histopathological information to trace tumor evolution both within the prostate and during metastasis...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: D. J. Woodcock, E. Riabchenko, S. Taavitsainen, M. Kankainen, G. Gundem, D. S. Brewer, P. Ellonen, M. Lepistö, Y. A. Golubeva, A. C. Warner, T. Tolonen, J. Jasu, W. B. Isaacs, M. R. Emmert-Buck, M. Nykter, T. Visakorpi, G. S. Bova, D. C. Wedge
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/6ef5ee7977814b898210580b5f7363d6
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:The evolutionary progression from primary to metastatic prostate cancer is largely uncharted, and the implications for liquid biopsy are unexplored. Here, the authors use deep genomic sequencing and histopathological information to trace tumor evolution both within the prostate and during metastasis in ten men.