Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy

The evolutionary progression from primary to metastatic prostate cancer is largely uncharted, and the implications for liquid biopsy are unexplored. Here, the authors use deep genomic sequencing and histopathological information to trace tumor evolution both within the prostate and during metastasis...

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Autores principales: D. J. Woodcock, E. Riabchenko, S. Taavitsainen, M. Kankainen, G. Gundem, D. S. Brewer, P. Ellonen, M. Lepistö, Y. A. Golubeva, A. C. Warner, T. Tolonen, J. Jasu, W. B. Isaacs, M. R. Emmert-Buck, M. Nykter, T. Visakorpi, G. S. Bova, D. C. Wedge
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/6ef5ee7977814b898210580b5f7363d6
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