Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization

Here, the authors employ Raman-Activated Cell Sorting (RACS) and metagenomics to identify organisms that can forage on O-glycan monosaccharides in the mouse gut, which they use to construct a bacterial consortium able to reduce Clostridioides difficile colonization based on competition for mucosal s...

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Autores principales:	Fátima C. Pereira, Kenneth Wasmund, Iva Cobankovic, Nico Jehmlich, Craig W. Herbold, Kang Soo Lee, Barbara Sziranyi, Cornelia Vesely, Thomas Decker, Roman Stocker, Benedikt Warth, Martin von Bergen, Michael Wagner, David Berry
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6eff2e3043044c8ca42169a7dde44167
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spelling	oai:doaj.org-article:6eff2e3043044c8ca42169a7dde441672021-12-02T18:01:42ZRational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization10.1038/s41467-020-18928-12041-1723https://doaj.org/article/6eff2e3043044c8ca42169a7dde441672020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18928-1https://doaj.org/toc/2041-1723Here, the authors employ Raman-Activated Cell Sorting (RACS) and metagenomics to identify organisms that can forage on O-glycan monosaccharides in the mouse gut, which they use to construct a bacterial consortium able to reduce Clostridioides difficile colonization based on competition for mucosal sugars.Fátima C. PereiraKenneth WasmundIva CobankovicNico JehmlichCraig W. HerboldKang Soo LeeBarbara SziranyiCornelia VeselyThomas DeckerRoman StockerBenedikt WarthMartin von BergenMichael WagnerDavid BerryNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fátima C. Pereira Kenneth Wasmund Iva Cobankovic Nico Jehmlich Craig W. Herbold Kang Soo Lee Barbara Sziranyi Cornelia Vesely Thomas Decker Roman Stocker Benedikt Warth Martin von Bergen Michael Wagner David Berry Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization
description	Here, the authors employ Raman-Activated Cell Sorting (RACS) and metagenomics to identify organisms that can forage on O-glycan monosaccharides in the mouse gut, which they use to construct a bacterial consortium able to reduce Clostridioides difficile colonization based on competition for mucosal sugars.
format	article
author	Fátima C. Pereira Kenneth Wasmund Iva Cobankovic Nico Jehmlich Craig W. Herbold Kang Soo Lee Barbara Sziranyi Cornelia Vesely Thomas Decker Roman Stocker Benedikt Warth Martin von Bergen Michael Wagner David Berry
author_facet	Fátima C. Pereira Kenneth Wasmund Iva Cobankovic Nico Jehmlich Craig W. Herbold Kang Soo Lee Barbara Sziranyi Cornelia Vesely Thomas Decker Roman Stocker Benedikt Warth Martin von Bergen Michael Wagner David Berry
author_sort	Fátima C. Pereira
title	Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization
title_short	Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization
title_full	Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization
title_fullStr	Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization
title_full_unstemmed	Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization
title_sort	rational design of a microbial consortium of mucosal sugar utilizers reduces clostridiodes difficile colonization
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6eff2e3043044c8ca42169a7dde44167
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Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization

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