PCP and Wnt pathway components act in parallel during zebrafish mechanosensory hair cell orientation

Planar cell polarity (PCP) regulates hair cell orientation in the zebrafish lateral line. Here, the authors show that mutating Wnt pathway genes (wnt11f1, fzd7a/b, and gpc4) causes concentric hair cell patterns not regulated by PCP, thus showing PCP/Wnt pathway genes have different consequences on h...

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Auteurs principaux: Joaquin Navajas Acedo, Matthew G. Voas, Richard Alexander, Thomas Woolley, Jay R. Unruh, Hua Li, Cecilia Moens, Tatjana Piotrowski
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/6f012fa95fe24ae2a2db36aed2fcdecd
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