Unique transcriptional profile of sustained ligand-activated preconditioning in pre- and post-ischemic myocardium.

Unique transcriptional profile of sustained ligand-activated preconditioning in pre- and post-ischemic myocardium.

<h4>Background</h4>Opioidergic SLP (sustained ligand-activated preconditioning) induced by 3-5 days of opioid receptor (OR) agonism induces persistent protection against ischemia-reperfusion (I-R) injury in young and aged hearts, and is mechanistically distinct from conventional precondi...

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Autores principales: Kevin J Ashton, Amanda Tupicoff, Grant Williams-Pritchard, Can J Kiessling, Louise E See Hoe, John P Headrick, Jason N Peart
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/6f05704634eb4f2c89a187de9c1c4886
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