Unique transcriptional profile of sustained ligand-activated preconditioning in pre- and post-ischemic myocardium.
<h4>Background</h4>Opioidergic SLP (sustained ligand-activated preconditioning) induced by 3-5 days of opioid receptor (OR) agonism induces persistent protection against ischemia-reperfusion (I-R) injury in young and aged hearts, and is mechanistically distinct from conventional precondi...
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Main Authors: | Kevin J Ashton, Amanda Tupicoff, Grant Williams-Pritchard, Can J Kiessling, Louise E See Hoe, John P Headrick, Jason N Peart |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/6f05704634eb4f2c89a187de9c1c4886 |
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