Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018

Abstract Norovirus is the leading cause of outbreaks of acute viral gastroenteritis. We carried out this study to investigate outbreaks in long-term care facilities reported in 2017 and 2018 in Catalonia (Spain). The characteristics of the centers, exposed persons and the genogroups responsible were...

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Autores principales:	Ignacio Parrón, Irene Barrabeig, Miquel Alseda, Cristina Rius, Thais Cornejo-Sánchez, Mireia Jané, Cristina Pérez, Susana Guix, Àngela Domínguez, the Working Group for the Study of Outbreaks of Acute Gastroenteritis in Catalonia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6f0bdee919a7458fae300289dc57f768
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spelling	oai:doaj.org-article:6f0bdee919a7458fae300289dc57f7682021-12-05T12:13:54ZNorovirus outbreaks in long-term care facilities in Catalonia from 2017 to 201810.1038/s41598-021-02348-22045-2322https://doaj.org/article/6f0bdee919a7458fae300289dc57f7682021-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02348-2https://doaj.org/toc/2045-2322Abstract Norovirus is the leading cause of outbreaks of acute viral gastroenteritis. We carried out this study to investigate outbreaks in long-term care facilities reported in 2017 and 2018 in Catalonia (Spain). The characteristics of the centers, exposed persons and the genogroups responsible were analyzed. Viral loads were estimated. The attack rate (AR) of the outbreaks studied, and the rate ratio (RR) and the odds ratio (OR) and their 95% confidence intervals as measures of association were calculated. The mean cycle thresholds were compared using the t-test for independent means. We included 30 outbreaks (4631 exposed people). The global AR was 25.93%. The RR of residents vs. staff was 2.28 (95% CI 2.0–2.6). The RR between AR in residents with total or severe dependence vs. residents with moderate, low or no-dependence was 1.23 (95% CI 1.05–1.45). The AR were higher in smaller centers than in larger ones (38.47% vs. 19.25% and RR 2; 95% CI 1.82–2.2). GII was responsible for 70% of outbreaks. No association was found between the genogroup and presenting symptoms (OR 0.96; 95% CI 0.41–2.26). Viral loads were higher in symptomatic than in asymptomatic patients (p = 0.001).Ignacio ParrónIrene BarrabeigMiquel AlsedaCristina RiusThais Cornejo-SánchezMireia JanéCristina PérezSusana GuixÀngela Domínguezthe Working Group for the Study of Outbreaks of Acute Gastroenteritis in CataloniaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ignacio Parrón Irene Barrabeig Miquel Alseda Cristina Rius Thais Cornejo-Sánchez Mireia Jané Cristina Pérez Susana Guix Àngela Domínguez the Working Group for the Study of Outbreaks of Acute Gastroenteritis in Catalonia Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018
description	Abstract Norovirus is the leading cause of outbreaks of acute viral gastroenteritis. We carried out this study to investigate outbreaks in long-term care facilities reported in 2017 and 2018 in Catalonia (Spain). The characteristics of the centers, exposed persons and the genogroups responsible were analyzed. Viral loads were estimated. The attack rate (AR) of the outbreaks studied, and the rate ratio (RR) and the odds ratio (OR) and their 95% confidence intervals as measures of association were calculated. The mean cycle thresholds were compared using the t-test for independent means. We included 30 outbreaks (4631 exposed people). The global AR was 25.93%. The RR of residents vs. staff was 2.28 (95% CI 2.0–2.6). The RR between AR in residents with total or severe dependence vs. residents with moderate, low or no-dependence was 1.23 (95% CI 1.05–1.45). The AR were higher in smaller centers than in larger ones (38.47% vs. 19.25% and RR 2; 95% CI 1.82–2.2). GII was responsible for 70% of outbreaks. No association was found between the genogroup and presenting symptoms (OR 0.96; 95% CI 0.41–2.26). Viral loads were higher in symptomatic than in asymptomatic patients (p = 0.001).
format	article
author	Ignacio Parrón Irene Barrabeig Miquel Alseda Cristina Rius Thais Cornejo-Sánchez Mireia Jané Cristina Pérez Susana Guix Àngela Domínguez the Working Group for the Study of Outbreaks of Acute Gastroenteritis in Catalonia
author_facet	Ignacio Parrón Irene Barrabeig Miquel Alseda Cristina Rius Thais Cornejo-Sánchez Mireia Jané Cristina Pérez Susana Guix Àngela Domínguez the Working Group for the Study of Outbreaks of Acute Gastroenteritis in Catalonia
author_sort	Ignacio Parrón
title	Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018
title_short	Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018
title_full	Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018
title_fullStr	Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018
title_full_unstemmed	Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018
title_sort	norovirus outbreaks in long-term care facilities in catalonia from 2017 to 2018
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6f0bdee919a7458fae300289dc57f768
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Norovirus outbreaks in long-term care facilities in Catalonia from 2017 to 2018

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