Anxiolytic effect of the extract from Rhaponticum uniflorum roots

The experiments were carried out on white Wistar rats. The dry extract from Rhaponticum uniflorum L. roots was administered to the animals at the doses of 200 and 300 mg/kg for 7 days before testing. The behavior of animals was observed with the use of the tests "elevated plus maze" (EPM)...

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Autores principales: N. K. Tatarinova, Y. G. Razuvaeva, L. N. Shantanova
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2015
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Acceso en línea:https://doaj.org/article/6f113e6899b346e291a7e3b76223b4ba
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spelling oai:doaj.org-article:6f113e6899b346e291a7e3b76223b4ba2021-11-23T06:14:32ZAnxiolytic effect of the extract from Rhaponticum uniflorum roots2541-94202587-9596https://doaj.org/article/6f113e6899b346e291a7e3b76223b4ba2015-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/40https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The experiments were carried out on white Wistar rats. The dry extract from Rhaponticum uniflorum L. roots was administered to the animals at the doses of 200 and 300 mg/kg for 7 days before testing. The behavior of animals was observed with the use of the tests "elevated plus maze" (EPM) and "dark/ light chamber". Under the influence of the extract from Rhaponticum uniflorum L. at the doses of 100, 150 and 250 mg/kg the number of entries into the open branch of EPM rises to 2,0-3,0 times and staying period in them rises 3,1-4,1 times in comparison with the control. The test "dark/light chamber" has shown that the number of entries of the experimental animals into the light bay of the "dark/light chamber" and the period of staying in it is 2,0 times increased.N. K. TatarinovaY. G. RazuvaevaL. N. ShantanovaScientific Сentre for Family Health and Human Reproduction Problemsarticleextract from rhaponticum uniflorum l. rootsanxiolytic effectScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2, Pp 92-94 (2015)
institution DOAJ
collection DOAJ
language RU
topic extract from rhaponticum uniflorum l. roots
anxiolytic effect
Science
Q
spellingShingle extract from rhaponticum uniflorum l. roots
anxiolytic effect
Science
Q
N. K. Tatarinova
Y. G. Razuvaeva
L. N. Shantanova
Anxiolytic effect of the extract from Rhaponticum uniflorum roots
description The experiments were carried out on white Wistar rats. The dry extract from Rhaponticum uniflorum L. roots was administered to the animals at the doses of 200 and 300 mg/kg for 7 days before testing. The behavior of animals was observed with the use of the tests "elevated plus maze" (EPM) and "dark/ light chamber". Under the influence of the extract from Rhaponticum uniflorum L. at the doses of 100, 150 and 250 mg/kg the number of entries into the open branch of EPM rises to 2,0-3,0 times and staying period in them rises 3,1-4,1 times in comparison with the control. The test "dark/light chamber" has shown that the number of entries of the experimental animals into the light bay of the "dark/light chamber" and the period of staying in it is 2,0 times increased.
format article
author N. K. Tatarinova
Y. G. Razuvaeva
L. N. Shantanova
author_facet N. K. Tatarinova
Y. G. Razuvaeva
L. N. Shantanova
author_sort N. K. Tatarinova
title Anxiolytic effect of the extract from Rhaponticum uniflorum roots
title_short Anxiolytic effect of the extract from Rhaponticum uniflorum roots
title_full Anxiolytic effect of the extract from Rhaponticum uniflorum roots
title_fullStr Anxiolytic effect of the extract from Rhaponticum uniflorum roots
title_full_unstemmed Anxiolytic effect of the extract from Rhaponticum uniflorum roots
title_sort anxiolytic effect of the extract from rhaponticum uniflorum roots
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2015
url https://doaj.org/article/6f113e6899b346e291a7e3b76223b4ba
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