Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells

Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells

Faecal microbiota transplantation (FMT) is becoming a therapeutic option in several gastrointestinal disorders. Here, Burrello et al. study the immunological mechanisms by which FMT reduces colonic inflammation and initiates the restoration of intestinal homeostasis in a mouse model of colitis.

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Autores principales: Claudia Burrello, Federica Garavaglia, Fulvia Milena Cribiù, Giulia Ercoli, Gianluca Lopez, Jacopo Troisi, Angelo Colucci, Silvia Guglietta, Sara Carloni, Simone Guglielmetti, Valentina Taverniti, Giulia Nizzoli, Silvano Bosari, Flavio Caprioli, Maria Rescigno, Federica Facciotti
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
Q
Acceso en línea:https://doaj.org/article/6f140d01828f4beeb27e25c2efa5c440
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spelling oai:doaj.org-article:6f140d01828f4beeb27e25c2efa5c4402021-12-02T13:24:34ZTherapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells10.1038/s41467-018-07359-82041-1723https://doaj.org/article/6f140d01828f4beeb27e25c2efa5c4402018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07359-8https://doaj.org/toc/2041-1723Faecal microbiota transplantation (FMT) is becoming a therapeutic option in several gastrointestinal disorders. Here, Burrello et al. study the immunological mechanisms by which FMT reduces colonic inflammation and initiates the restoration of intestinal homeostasis in a mouse model of colitis.Claudia BurrelloFederica GaravagliaFulvia Milena CribiùGiulia ErcoliGianluca LopezJacopo TroisiAngelo ColucciSilvia GugliettaSara CarloniSimone GuglielmettiValentina TavernitiGiulia NizzoliSilvano BosariFlavio CaprioliMaria RescignoFederica FacciottiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Claudia Burrello
Federica Garavaglia
Fulvia Milena Cribiù
Giulia Ercoli
Gianluca Lopez
Jacopo Troisi
Angelo Colucci
Silvia Guglietta
Sara Carloni
Simone Guglielmetti
Valentina Taverniti
Giulia Nizzoli
Silvano Bosari
Flavio Caprioli
Maria Rescigno
Federica Facciotti
Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells
description Faecal microbiota transplantation (FMT) is becoming a therapeutic option in several gastrointestinal disorders. Here, Burrello et al. study the immunological mechanisms by which FMT reduces colonic inflammation and initiates the restoration of intestinal homeostasis in a mouse model of colitis.
format article
author Claudia Burrello
Federica Garavaglia
Fulvia Milena Cribiù
Giulia Ercoli
Gianluca Lopez
Jacopo Troisi
Angelo Colucci
Silvia Guglietta
Sara Carloni
Simone Guglielmetti
Valentina Taverniti
Giulia Nizzoli
Silvano Bosari
Flavio Caprioli
Maria Rescigno
Federica Facciotti
author_facet Claudia Burrello
Federica Garavaglia
Fulvia Milena Cribiù
Giulia Ercoli
Gianluca Lopez
Jacopo Troisi
Angelo Colucci
Silvia Guglietta
Sara Carloni
Simone Guglielmetti
Valentina Taverniti
Giulia Nizzoli
Silvano Bosari
Flavio Caprioli
Maria Rescigno
Federica Facciotti
author_sort Claudia Burrello
title Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells
title_short Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells
title_full Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells
title_fullStr Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells
title_full_unstemmed Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells
title_sort therapeutic faecal microbiota transplantation controls intestinal inflammation through il10 secretion by immune cells
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/6f140d01828f4beeb27e25c2efa5c440
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