CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells.

CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells.

While CD8+ T cells are clearly important in controlling virus replication during HIV and SIV infections, the mechanisms underlying this antiviral effect remain poorly understood. In this study, we assessed the in vivo effect of CD8+ lymphocyte depletion on the lifespan of productively infected cells...

Full description

Saved in:
Bibliographic Details
Main Authors: Nichole R Klatt, Emi Shudo, Alex M Ortiz, Jessica C Engram, Mirko Paiardini, Benton Lawson, Michael D Miller, James Else, Ivona Pandrea, Jacob D Estes, Cristian Apetrei, Joern E Schmitz, Ruy M Ribeiro, Alan S Perelson, Guido Silvestri
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/6f185ff767e24750be4e4e2808b53271
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/6f185ff767e24750be4e4e2808b53271

Similar Items