CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells.

CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells.

While CD8+ T cells are clearly important in controlling virus replication during HIV and SIV infections, the mechanisms underlying this antiviral effect remain poorly understood. In this study, we assessed the in vivo effect of CD8+ lymphocyte depletion on the lifespan of productively infected cells...

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Detalles Bibliográficos
Autores principales: Nichole R Klatt, Emi Shudo, Alex M Ortiz, Jessica C Engram, Mirko Paiardini, Benton Lawson, Michael D Miller, James Else, Ivona Pandrea, Jacob D Estes, Cristian Apetrei, Joern E Schmitz, Ruy M Ribeiro, Alan S Perelson, Guido Silvestri
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/6f185ff767e24750be4e4e2808b53271
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https://doaj.org/article/6f185ff767e24750be4e4e2808b53271

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