A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission

Mosquito saliva can affect transmission of Plasmodium to mammalian hosts, but active saliva components or mechanisms are poorly understood. Here, the authors identify a mosquito saliva protein that binds Plasmodium sporozoites and inhibits cell traversal in vitro and sporozoite speed in mice.

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Autores principales:	Tyler R. Schleicher, Jing Yang, Marianna Freudzon, Alison Rembisz, Samuel Craft, Madeleine Hamilton, Morven Graham, Godfree Mlambo, Abhai K. Tripathi, Yue Li, Peter Cresswell, Photini Sinnis, George Dimopoulos, Erol Fikrig
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6f1de94305704e90b23021c6aaa9d413
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spelling	oai:doaj.org-article:6f1de94305704e90b23021c6aaa9d4132021-12-02T16:49:22ZA mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission10.1038/s41467-018-05374-32041-1723https://doaj.org/article/6f1de94305704e90b23021c6aaa9d4132018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05374-3https://doaj.org/toc/2041-1723Mosquito saliva can affect transmission of Plasmodium to mammalian hosts, but active saliva components or mechanisms are poorly understood. Here, the authors identify a mosquito saliva protein that binds Plasmodium sporozoites and inhibits cell traversal in vitro and sporozoite speed in mice.Tyler R. SchleicherJing YangMarianna FreudzonAlison RembiszSamuel CraftMadeleine HamiltonMorven GrahamGodfree MlamboAbhai K. TripathiYue LiPeter CresswellPhotini SinnisGeorge DimopoulosErol FikrigNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tyler R. Schleicher Jing Yang Marianna Freudzon Alison Rembisz Samuel Craft Madeleine Hamilton Morven Graham Godfree Mlambo Abhai K. Tripathi Yue Li Peter Cresswell Photini Sinnis George Dimopoulos Erol Fikrig A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission
description	Mosquito saliva can affect transmission of Plasmodium to mammalian hosts, but active saliva components or mechanisms are poorly understood. Here, the authors identify a mosquito saliva protein that binds Plasmodium sporozoites and inhibits cell traversal in vitro and sporozoite speed in mice.
format	article
author	Tyler R. Schleicher Jing Yang Marianna Freudzon Alison Rembisz Samuel Craft Madeleine Hamilton Morven Graham Godfree Mlambo Abhai K. Tripathi Yue Li Peter Cresswell Photini Sinnis George Dimopoulos Erol Fikrig
author_facet	Tyler R. Schleicher Jing Yang Marianna Freudzon Alison Rembisz Samuel Craft Madeleine Hamilton Morven Graham Godfree Mlambo Abhai K. Tripathi Yue Li Peter Cresswell Photini Sinnis George Dimopoulos Erol Fikrig
author_sort	Tyler R. Schleicher
title	A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission
title_short	A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission
title_full	A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission
title_fullStr	A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission
title_full_unstemmed	A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission
title_sort	mosquito salivary gland protein partially inhibits plasmodium sporozoite cell traversal and transmission
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/6f1de94305704e90b23021c6aaa9d413
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A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission

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